Results 121 to 130 of about 30,769 (308)
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Integrating Lean Manufacturing and Industry 4.0 for Enhanced Operational Performance [PDF]
openThis thesis examines the integration of Lean Manufacturing principles with Industry 4.0 technologies and their combined impact on organizational performance. The first chapter provides a brief overview of Lean manufacturing.
FILIPUZZI, GIULIA
core
Application of lean manufacturing tools: a case study in a mattress factory [PDF]
, 2019 Lean manufacturing is a production strategy that aims to reduce waste and increase value added through the application of tools of the Lean philosophy, such as: Value Flow-MFV Mapping, 5S Program and Standardization of Labor.
Silva, Camila de Cássia Mendonça +4 more
core
The Lean Design of Manufacturing Process
Contemporary Economics, 2008 This article is intended to using of Six Sigma methodology. A break trough strategy to significantly improve customer satisfaction and shareholder value by reducing variability in every aspects of business. It enhances the ability to delivery customer satisfaction and cost improvement results faster – within months from the start, and sustains the rate
openaire +4 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Beyond Lean: Simulation in Practice, Second Edition
, 2013 Lean thinking, as well as associated processes and tools, have involved into a ubiquitous perspective for improving systems particularly in the manufacturing arena.
Standridge, Charles R., Ph.D.
core
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Investigating the readiness of people in manufacturing SMEs to embark on LSS projects
, 2014 Purpose – The purpose of this article is to investigate the impact of the core personal competence, vision and organisational culture on readiness of people to commence Lean Six Sigma (LSS) projects in the manufacturing Small and Medium Sized ...
Shokri, Alireza, Libenthal, Artem
core
Management System EngineeringCurrently globally industries are increasingly adopting lean production methods to enhance operational efficiency and overall business performance. Lean tools, which significantly reduce waste, are particularly beneficial for small and medium enterprises
Juma M. Matindana, Mary J. Shoshiwa
doaj +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source