Results 111 to 120 of about 3,957,535 (355)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Measuring and monitoring lean body mass in critical illness

Current Opinion in Critical Care, 2018
Purpose of review To help guide metabolic support in critical care, an understanding of patients’ nutritional status and risk is important. Several methods to monitor lean body mass are increasingly used in the ICU and knowledge about their advantages and limitations is essential.
Looijaard, Wilhelmus G P M, Molinger, Jeroen, Weijs, Peter J M   +2 more
openaire   +6 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Effects of Resistance Exercise on Total and Regional Body Composition in Overweight Sedentary Males

Spor Bilimleri Araştırmaları Dergisi
The purpose of this study was to examine the effects of 12 weeks of resistance exercise training on body weight (BW), body mass index (BMI), total fat mass (FM), trunk, arm, and leg fat mass, and total lean body mass (LBM), arm, and leg lean mass of ...
Halil Tanır, Bahar Ateş, Jorge Mota, Lucimere Bohn   +3 more
doaj   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Impact of creatine supplementation in combination with resistance training on lean mass in the elderly

Journal of Cachexia, Sarcopenia and Muscle, 2016
Human ageing is a process characterized by loss of muscle mass, strength, and bone mass. We aimed to examine the efficacy of low‐dose creatine supplementation associated with resistance training on lean mass, strength, and bone mass in the elderly.
Camila L. P. Oliveira, P. Botelho, J. A. Carneiro, J. F. Mota   +3 more
semanticscholar   +1 more source

Growth and Growth Velocity of Lean Body Mass and Fat in Adolescent Boys [PDF]

, 1976
Jana Pařízková
openalex   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

LEAN PRODUCTION, LEAN VS. MASS PRODUCTION, TPM AS A TOOL OF LEAN PRODUCTION

Perner’s Contacts, 2011
Article discusses the key feature of lean production, its basic objectives, advantages. Next article describes the differences between mass production and lean production.
Mária Mičietová
doaj  

Serum uric acid-its relationship to lean body mass sex, plasma urea, intracellular potassium and packed cell volume in a normal population group. [PDF]

, 1975
A. C. Kennedy, Jennifer Brennan, J. A. R. ANDERSON, Philip J. Brooks, W. Watson Buchanan, W. Carson Dick   +5 more
openalex   +1 more source