Results 71 to 80 of about 3,455,968 (292)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Contributions of lean mass and fat mass to bone mineral density: a study in postmenopausal women
BMC Musculoskeletal Disorders, 2010 Background The relative contribution of lean and fat to the determination of bone mineral density (BMD) in postmenopausal women is a contentious issue. The present study was undertaken to test the hypothesis that lean mass is a better determinant of BMD ...
Lai Thai Q +3 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Factors Associated With Low Lean Mass in Early Rheumatoid Arthritis: A Cross- Sectional Study
Medicina, 2019 Background and Objectives: The aim of the study was to evaluate body composition (BC) of rheumatoid arthritis (RA) patients at disease onset compared to population controls focusing on the associations between low lean mass and disease specific ...
Raili Müller +5 more
doaj +1 more source
Succinylcholine dosage based on lean body mass [PDF]
Canadian Anaesthetists’ Society Journal, 1972 Although the dose of succinylcholine is customarily based on body weight this can be taken only as a rough guide. In the early phase after intravenous injection succinylcholine is partly removed by breakdown through the action of cholinesterase and in part by redistribution into the lean body mass. Sixty-six patients were given doses of succinylcholine
openaire +2 more sources
Lean body mass in children with cystic fibrosis [PDF]
Archives of Disease in Childhood, 2003 Poor nutritional status adversely affects long term survival of patients with cystic fibrosis (CF).1 Body composition measured by dual energy x ray absorptiometry (DXA) has been shown to correlate well with other established techniques such as bioelectric impedance analysis and total body potassium estimation.2 This study was designed to compare the ...
M, Sood, J E, Adams, M Z, Mughal
openaire +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
International Journal of Women's Health, 2013 Sirianong Namwongprom,1 Sattaya Rojanasthien,2 Ampica Mangklabruks,3 Supasil Soontrapa,4 Chanpen Wongboontan,5 Boonsong Ongphiphadhanakul61Clinical Epidemiology Program and Department of Radiology, 2Department of Orthopaedics, 3Department of Internal ...
Namwongprom S +5 more
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Consequências da implantação pontual de ferramentas Lean [PDF]
, 2016 A manufatura lean vem sendo amplamente discutida e difundida desde os primórdios de sua criação. Entretanto, este enfoque produz alguns efeitos contrários, como o problema das empresas que não adotam a filosofia como um todo utilizando apenas algumas ...
Ferreira, Caio Cesar +4 more
core +1 more source