Results 31 to 40 of about 111,920 (305)

Innovation and Lean Production

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2018
Production has undergone historically through different changes, the essence of which is innovation. Innovations are either the introduction of new and more powerful machines and technologies, or just tiny, but everyday changes called Kaizen. The article
Drahoš Vaněček   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Expertise in applying lean manufacturing tools to reduce costs of the pipe chemical processing

open access: yesОмский научный вестник
This article presents results of the use of lean production methods and tools to ensure improvement of efficiency of the pipes chemical processing process at JSC “Volga Pipe Plant”.
N. D. Prokopenko   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Implementing Lean Production – Application of Little’s Law

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016
This article is about implementing lean production in a company and problems with this process. Firstly it focuses on the definition of lean production.
Michal Medonos, Marie Jurová
doaj   +1 more source

An adaptive method for assessing the implementation degree of lean production [PDF]

open access: yes, 2020
The implementation of lean production is a continuous improvement process that requires the assessment of its progress over time. On the other hand, adaptations to the implementation and assessment of lean production are usually necessary, since each ...
Vilar, Flora Magna do Monte   +1 more
core  

Towards lean product and process development [PDF]

open access: yes, 2013
Successes in lean manufacture have led researchers and practitioners to consider extending ‘lean' to different parts of the engineering enterprise, including product and process development (PPD). Lean product development (PD) has been understood to mean
Amaia Sopelana   +15 more
core   +1 more source

Opportunities for implementation of concepts and tools lean production aiming to improve competitiveness of enterprises of shoe APL Jaú / SP

open access: yesRevista Produção Online, 2013
Lean production has been applied by organizations around the world as part of strategy to reduce waste in their value stream intending to improve performance.
Célio Favoni   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Intelligent Products: Shifting the Production Control Logic in Construction (With Lean and BIM) [PDF]

open access: yes, 2015
Production management and control in construction has not been addressed/updated ever since the introduction of Critical Path Method and the Last Planner® system.
Holmström, Jan   +7 more
core  

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