Results 51 to 60 of about 530,707 (357)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Automation from lean perspective-potentials and challenges [PDF]

open access: yes, 2013
The competitive climate of production and high labour cost, motivate western companies to use technologies like automation as a mean to increase manufacturing competitiveness.
Jackson, Mats, Zafarzadeh, Masoud
core  

Lean Warehousing: Enhancing Productivity Through Lean

open access: yes, 2021
The environment dynamism of the modern era is fostering the spreading of lean in every industry. Followed by the demonstrated benefits of the lean principles in operational performances many companies have taken the leap. Nonetheless, beyond the manufacturing and mass production industries, the dissemination of lean has a long road ahead yet.
Rossini M.   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Implementation of lean leadership

open access: yesManagement, 2016
The Toyota case proves that lean leadership is of critical importance for the successful implementation and permanent functioning of Lean Production System. There is no ready formula for developing Toyota style lean leadership.
Trenkner Małgorzata
doaj   +1 more source

Towards an Operational Definition of Lean Construction Onsite [PDF]

open access: yes, 2015
Through literature review and drawing from a combined professional experience of over 20 years of lean construction implementation, this paper investigates the key success factor for the automotive industry’s uptake of lean production to see what the ...
Koskela, Lauri   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Concept of Japanese Culture in Lean Production of the Toyota Automobile Company: Its Scientific Development and Application in Higher Education and Agriculture [PDF]

open access: yesJurnal Japanedu: Pendidikan dan Pengajaran Bahasa Jepang, 2023
The purpose of the article is to create a scientific theory of lean production of goods and services (the theory of thrift), from the perspective of Japanese culture which is applicable in higher education and agriculture. Currently, a new technological
Valery Vladimirovich Glushchenko
doaj  

From Lean Production to Lean 4.0: A Systematic Literature Review with a Historical Perspective

open access: yesApplied Sciences, 2021
Over recent decades, the increasing competitiveness of markets has propagated the term “lean” to describe the management concept for improving productivity, quality, and lead time in industrial as well as services operations.
Francisco Gil-Vilda   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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