Results 51 to 60 of about 111,920 (305)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Lean Production in Germany [PDF]
, 2021 The first publications on lean production and the evidence of the competitive advantage Japanese companies held over German competitors (Womack et al. 1990) shocked the German automotive industry of the late 1980s and early 1990s, leading to difficult discussions within companies, trade unions and the academic community about the future development of ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Lean production: il caso Fischer Italia
, 2022 L'elaborato consiste nell'esposizione dei concetti e degli strumenti della "filosofia gestionale applicata" nota come lean production, proponendo in ultima un caso aziendale ...
Bianco, Dario
core
Новые технологии, 2019 The problems of the regional investment sector have been assessed in the article using lean production tools. Methods of solving problems using lean production tools include identifying and formulating the causes of problems (deviations), developing ...
G. V. Karamushko, N. G. Maskova
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Implementation of lean manufacturing [PDF]
, 2004 Plan BLean manufacturing refers to a manufacturing improvement process based on the fundamental goal of Toyota production system (TPS) in order to minimize or eliminate waste while maximizing production flow (Tapping, 2002).
Tinoco, Juan C.
core
Lean Philosophy in Agricultural Production: A Literature Review on Türkiye
Journal of Agricultural SciencesThis study is a review article that addresses the potential of lean production philosophy to reduce waste and increase process efficiency in the manufacturing processes of agricultural products.
Selçuk Özcan, Zeynep Kulaksız
doaj +1 more source