Results 71 to 80 of about 6,262,714 (282)
Integrating Lean Principles into Lean Robotics Systems for Enhanced Production Processes
Integrating lean principles into lean robotics systems emerges as a transformative path for production processes. This paper addresses the question of what are the best practices of integrating lean principles within robotics systems to enhance ...
Stelian Brad, Eyas Deeb
doaj +1 more source
MES Support for Lean Production [PDF]
In the traditional sense, IT has often been viewed as a contributor to waste within lean production. However, as the business world changes and competition from low-cost countries increases, new models must be developed which deliver competitive advantage by combining contemporary technological advances with the lean paradigm.
Daryl Powell +2 more
openaire +3 more sources
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEATURES OF IMPLEMENTING LEAN PRODUCTION IN SOCIAL ESTABLISHMENTS
Objective: to disseminate ideas and principles of implementing the methodology of lean production. Methods: practical approaches to implementing the tools of lean production in social establishments.
I. I. Antonova +2 more
doaj
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Lean production: il caso Fischer Italia
L'elaborato consiste nell'esposizione dei concetti e degli strumenti della "filosofia gestionale applicata" nota come lean production, proponendo in ultima un caso aziendale ...
Bianco, Dario
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Implementation of lean manufacturing [PDF]
Plan BLean manufacturing refers to a manufacturing improvement process based on the fundamental goal of Toyota production system (TPS) in order to minimize or eliminate waste while maximizing production flow (Tapping, 2002).
Tinoco, Juan C.
core

