Results 81 to 90 of about 6,262,714 (282)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Advances in Civil Engineering, 2020 Component factories are experiencing the problems associated with lean production, especially the accuracy of production time prediction and the unnecessary waste in terms of time and resource utilization.
Zhenmin Yuan +5 more
doaj +1 more source
A Model of Lean Supplier Management Based on the Lean Production [PDF]
, 2007 In this paper, we present a model of lean supplier management between an OEM and its suppliers for the objectives of eliminating wastes, reducing cost and improvement continuously based on the lean production. This model includes supplier selection and categorization, supplier improvement, supplier certification and supplier evaluation.
Yixun Guo, Zhiduan Xu
openaire +2 more sources
Lean Product Development and the Role of PLM [PDF]
, 2016 Lean Product Development (LPD) promises high product development success by strongly relying on knowledge. Though, despite many IT-based knowledge management tools exist to support and enable knowledge capture, use, formalization and reuse in product development, such as Product Lifecycle Management (PLM) systems, their use within the LPD context is ...
Monica Rossi +5 more
openaire +2 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Modello giapponese, toyotismo, produzione snella: alcune questioni aperte
Quaderni di Sociologia, 1992 The paper argues that a distinction should be drawn between the Japanese Model and Lean Production. The first refers to the sum of social and cultural aspects of the Japanese traditional way of managing human resourses, whereas the second refers to the ...
Giuseppe Bonazzi
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Possibilities of visualization as a lean method in the management of medical organizations
Медицинский вестник Юга России, 2019 The article presents the results of a review of literature on the possibility of visualization in the health care system of the Russian Federation as one of the main methods of implementation of lean production.
Albert A. Kurmangulov +4 more
doaj +1 more source
Towards Creative Lean (Clean) Construction: From Lean Production to Lean Consumption [PDF]
Annual Conference of the International Group for Lean Construction, 2018 Peer ...
openaire +2 more sources