Results 111 to 120 of about 879,996 (370)
Examining Factory Process Safety Management Systems And Studying Lean Improvement Methods
Journal of Applied Engineering and Technological ScienceMany factories have set up a safety management system (PSM), and there is an increasing rate of safety management systems. This is increasingly in line with the development of industrial plants.
Bunphot Tepparit +2 more
doaj +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Development and Evolution of Agile – Changes in a World of Change [PDF]
Journal of Systemics, Cybernetics and Informatics, 2020 Agile software development is an approach first codified in the Agile Manifesto in 2001. This was a statement of core values that became associated with a set of principles and practices.
Thomas J. Marlowe +4 more
doaj
Book Reviews: Lean Software Development: An Agile Toolkit [PDF]
Queue, 2003 With brief examples based on the authors’ real-life experiences, the reader sees how “good software practice” in its traditional and literal sense can often lead to something between disaster and frustration. In particular, the authors argue that specifying a software system in its entirety before developing any code, ensures there is no flexibility ...
openaire +1 more source
DevOps is Bigger than IT: Driving Digital Transformation in Libraries [PDF]
, 2020 The DevOps movement represents a paradigm shift in software development, but there are misconceptions about what it really means. It’s much more nuanced than simply adding a DevOps engineer to your team or asking systems administrators and developers to ...
Snapp, Mary Beth, Vinopal, Jennifer
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
An Empirical Study on Leanness and Flexibility in Distributed Software Development [PDF]
, 2017 Mohammad Abdur Razzak
openalex +1 more source
Управління міжнародним бізнесом: Agility Journey для високотехнологічних компаній [PDF]
, 2019 The purpose of the article is the development of recommendations for the business maturity determination and measurement in the implementation of the agile approach for high-tech companies.
Rusanova, L. D. +1 more
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source