Results 51 to 60 of about 19,993,772 (359)
Learning Geometric Concepts with Nasty Noise
, 2017 We study the efficient learnability of geometric concept classes - specifically, low-degree polynomial threshold functions (PTFs) and intersections of halfspaces - when a fraction of the data is adversarially corrupted.
Daniely A. +3 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Smart learning futures: a report from the 3rd US-China smart education conference
Smart Learning Environments, 2018 The third day of the third US-China Smart Education Conference featured a discussion with 27 thinkers representing higher education, business and industry, vocational training, and policy making.
J. Michael Spector +1 more
doaj +1 more source
Machine Learning-Based Elastic Cloud Resource Provisioning in the Solvency II Framework [PDF]
, 2016 The Solvency II Directive (Directive 2009/138/EC) is a European Directive issued in November 2009 and effective from January 2016, which has been enacted by the European Union to regulate the insurance and reinsurance sector through the discipline of ...
Casarano, Giuseppe +5 more
core +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Conscientization, Dialogue and Collaborative Problem Based Learning
Journal of Problem Based Learning in Higher Education, 2013 It has been argued that Paulo Freire’s concept of conscientization, where critical awareness and engagement are central to a problem-posing pedagogy, provides the philosophical principles to underpin Problem Based Learning (PBL). By using dialogue groups
Conscientization, Dialogue and Collaborative Problem Based Learning
doaj
A machine learning forecasting model for COVID-19 pandemic in India [PDF]
, 2020 R. Sujath +2 more
openalex +1 more source