Results 91 to 100 of about 11,309,865 (308)

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Hearts on Our Sleeves: Emotions Experienced by Service-Learning Faculty [PDF]

, 2017
Compared to more traditional pedagogical approaches, service-learning has been shown to offer unique experiences for students and faculty. With the growth of service-learning within higher education, it has become increasingly important to understand ...
Lassiter, Jill W., Martin, Tiesha R., Lecrom, Carrie W.   +2 more
core  

Evaluating the community outcomes of Australian learning community initiatives: innovative approaches to assessing complex outcomes

, 2013
Learning communities are towns, cities, or regions where a series of actions are implemented to enhance lifelong learning and community capacity. These efforts include improving access to further education, mentoring, increasing opportunities for ...
Simmons, Jan, Herlihy, Paula, Cavaye, Jim, Wong, Shanti, Wheeler, Leone, Saleeba, Jim   +5 more
core   +1 more source

A longitudinal mixed methods evaluation of a facilitation training intervention to build implementation capacity

Frontiers in Health Services
BackgroundThere is a demand for facilitators who can ease the collaboration within a team or an organization in the implementation of evidence-based interventions (EBIs) and who are positioned to build the implementation capacity in an organization. This
Veronica-Aurelia Costea, Veronica-Aurelia Costea, Annika Bäck, Annika Bäck, Anna Bergström, Anna Bergström, Andreas Lundin, Henna Hasson, Henna Hasson, Leif Eriksson   +9 more
doaj   +1 more source

Transitional Writing and "Third Space" Learning: Professional Writing Students and the Work Experience

Discourse and Writing/Rédactologie, 2011
This paper is based on a long-term study of professional writing students in an internship, "work experience" course. Building upon work theorizing the problematic gap between classroom instruction and workplace practice, this study extends analysis to ...
Diana Wegner
doaj   +1 more source

A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham, Casey Vanderlip, Colin Birkenbihl, Eashwar Krishna, Chizobam Ugboaja, Andrew E. Budson, Brandon Frank, for the Alzheimer's Disease Neuroimaging Initiative   +7 more
wiley   +1 more source

Engineering Hybrid Learning Communities: The Case of a Regional Parent Community

Systems, 2014
We present an approach (and a corresponding system design) for supporting regionally bound hybrid learning communities (i.e., communities which combine traditional face-to-face elements with web based media such as online community platforms, e-mail and ...
Sven Strickroth, Niels Pinkwart
doaj   +1 more source

Community IT workshops as a strategy for community learning

First Monday, 2008
A university-community partnership to develop strategies for sustainable IT learning in local non-profit organizations initiated the Central Pennsylvania Community Information Technology Workshop series in 2003. The original goal was narrow and modest: To plan a set of participatory action research projects in which Penn State faculty and students ...
openaire   +2 more sources