Results 111 to 120 of about 801,663 (293)

Quality here, there and everywhere: the application of a multi-dimensional learning tool to learning disability health services [PDF]

open access: yes, 1999
The following paper examines the applicability of Maxwell’s (1984) Multi-dimensional Quality Evaluation model to community learning disability health services.
McKenzie, Karen   +3 more
core  

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

open access: yesAdvanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi   +5 more
wiley   +1 more source

Measurement issues in longitudinal studies of mental health problems in children with neurodevelopmental disorders

open access: yesBMC Psychology
Purpose To develop and test an approach for assessing the risk of bias in four measurement-related domains key to the study of mental health problem trajectories in children with neurodevelopmental disorders (NDD): (1) conceptual overlap between mental ...
Magnus Ivarsson   +2 more
doaj   +1 more source

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

open access: yesAdvanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol   +17 more
wiley   +1 more source

Evidencing the challenges of care delivery for people with intellectual disability and epilepsy in England by using the Step Together toolkit

open access: yesBJPsych Open
Background People with intellectual disability (PwID) and epilepsy have increased premature and potentially preventable mortality. This is related to a lack of equitable access to appropriate care.
Tom Shillito   +14 more
doaj   +1 more source

Habits of mind and the ability to solve problems among middle school students with learning disabilities [PDF]

open access: diamond, 2022
Rehab Hamdi Abdel Karim Al Abbasi   +2 more
openalex   +1 more source

Job Accommodations for People with Learning Disabilities [PDF]

open access: yes, 2007
[Excerpt] The term reasonable accommodation refers to changes in the workplace that enable people with disabilities to effectively perform the tasks associated with their job. Accommodations can help people with learning disabilities do their work well,
Brown, Dale Susan
core   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

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