Results 41 to 50 of about 784,360 (312)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Cognitive Shifting Ability Does Not Predict Self-Perceived Hearing Difficulties in Adult Hearing-Aid Users

Trends in Hearing
Age-related hearing loss (ARHL) often leads to hearing difficulties, impacting communication and daily functioning even among hearing-aid users. While hearing loss and cognitive functions, such as cognitive shifting ability, have been proposed as ...
Francesca Molinari Luccini, Henrik Danielsson, Victoria Stenbäck, Elaine Hoi Ning Ng, Emil Holmer   +4 more
doaj   +1 more source

Are We Ready for Fragile X Newborn Screening Testing?—Lessons Learnt from a Feasibility Study

International Journal of Neonatal Screening, 2018
Fragile X syndrome (FXS) is the most prevalent heritable cause of cognitive impairment but is not yet included in a newborn screening (NBS) program within Australia.
Tiffany Wotton, Veronica Wiley, Bruce Bennetts, Louise Christie, Bridget Wilcken, Gemma Jenkins, Carolyn Rogers, Jackie Boyle, Michael Field   +8 more
doaj   +1 more source

Knowledge of learning disabilities: the relationship with choice, duty of care and non-aversive approaches [PDF]

, 2007
The present study examines the relationship between the knowledge of the diagnostic criteria for a learning disability (based on DSM IV criteria), care practices and experience in health care and social care staff.
Higgon, John, Matheson, Edith, McKenzie, Karen, Murray, George   +3 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

A Glimpse of Memory Through the Eyes: Pupillary Responses Measured During Encoding Reflect the Likelihood of Subsequent Memory Recall in an Auditory Free Recall Test

Trends in Hearing, 2022
The aim of the current study was to investigate whether task-evoked pupillary responses measured during encoding, individual working memory capacity and noise reduction in hearing aids were associated with the likelihood of subsequently recalling an item
Andreea Micula, Jerker Rönnberg, Patrycja Książek, Reena Murmu Nielsen, Dorothea Wendt, Lorenz Fiedler, Elaine Hoi Ning Ng   +6 more
doaj   +1 more source

The changing of the guard: groupwork with people who have intellectual disabilities [PDF]

, 2009
This paper considers the impact of service systems on group activities. It describes an inter-professional groupwork project facilitated by a social worker and a community nurse.
A. McClimens, A. Mullender, B. Nirje, B.W. Tuckman, C. Barnes, C.J.G. Gersick, D. Cardore, D. Herd, D. Ward, D.G. Race, F. Kevan, H. Northen, J. Edge, J. Walmsley, J. Walmsley, K. Nichols, L. Staples, M. Cohen, M. Doel, M. Preston-Shoot, P. Reason, P. Trevithick, P. Williams, R. Burke, R. Smith, R. Townsley, R.J. Stancliffe, S-J. Hays, S. Read, S. Russell, S.H. Chia, T. MacKay, T. Tyson, W. Utting   +33 more
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

fMRI Evidence of Magnitude Manipulation during Numerical Order Processing in Congenitally Deaf Signers

Neural Plasticity, 2018
Congenital deafness is often compensated by early sign language use leading to typical language development with corresponding neural underpinnings.
Josefine Andin, Peter Fransson, Jerker Rönnberg, Mary Rudner   +3 more
doaj   +1 more source

Higher education provision for students with disabilities in Cyprus [PDF]

, 2007
Internationally, the number of students with disabilities entering higher education institutions is on the rise. Research estimates that 8–10% of students attending higher education are registered with disability, with learning difficulties being the ...
Hadjikakou, Kika, Hartas, Dimitra
core   +1 more source