Results 61 to 70 of about 6,779,968 (351)

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

The evaluation of a screening tool for children with an intellectual disability: The Child and Adolescent Intellectual Disability Screening Questionnaire [PDF]

open access: yes, 2012
The study outlines the evaluation of an intellectual disability screening tool, the Child and Adolescent Intellectual Disability Screening Questionnaire (CAIDS-Q), with two age groups.
Milanesi, Paula   +9 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Palliative care communication between patients with intellectual disabilities and hospice staff: a Conversation Analysis pilot study protocol

open access: yesBMJ Open
Introduction Communication challenges are among the main barriers for people with intellectual disabilities in accessing palliative care. They include inadequate skills among staff and difficulties with confirming understanding and around the ...
Irene Tuffrey-Wijne, Andrea Bruun
doaj   +1 more source

اثربخشی تقویت حافظه دیداری به طریق بازی درمانی بر کاهش خطاهای املایی دانش‌آموزان دارای اختلال نوشتن

open access: yesمجله پژوهش در علوم توانبخشی, 2012
مقدمه: در ارتباط با نقایص شناختی دانش‌آموزان مبتلا به اختلال نوشتن فرضیات متعددی وجود دارد که یکی از این فرضیات نقص در حافظه دیداری است. هدف از مطالعه حاضر، اثربخشی تقویت حافظه دیداری به طریق بازی درمانی بر کاهش خطاهای املایی دانش‌آموزان دارای اختلال ...
Akbar Abdi, Mahdi Karami, Javad Hatami
doaj   +1 more source

Perspectives from consultant nephrologists and families on how patients with a learning disability cope with chronic kidney diseases [PDF]

open access: yes, 2011
Healthcare for patients with a learning disability is an important topic; one that is receiving increased attention by the media, government, and NHS.
Read, Elspeth Mary
core  

Problems, problems: You are such a problem! [PDF]

open access: yes, 2009
A learning disability discourse has developed over time and is driven by social policy and professional power. Landmark legislation such as the Disability Discrimination Act 1995 has promoted public accessibility for disabled and disenfranchised people.
McAnelly, Su   +2 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Fact Retrieval Deficits in Low Achieving Children and Children with Mathematical Learning Disability

open access: yesJournal of Learning Disabilities, 2011
Using 4 years of mathematics achievement scores, groups of typically achieving children (n = 101) and low achieving children with mild (LA–mild fact retrieval; n = 97) and severe (LA–severe fact retrieval; n = 18) fact retrieval deficits and ...
D. Geary, Mary K. Hoard, Drew H. Bailey
semanticscholar   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

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