Results 21 to 30 of about 25,784,469 (265)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A prototype ETL pipeline that uses HL7 FHIR RDF resources when deploying pure functions to enrich knowledge graph patient data

Journal of Biomedical Semantics
Background For clinical care and research, knowledge graphs with patient data can be enriched by extracting parameters from a knowledge graph and then using them as inputs to compute new patient features with pure functions.
Adeel Ansari, Marisa Conte, Allen Flynn, Avanti Paturkar   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Interactive learning objects as a solution to challenges in basic medical science teaching

African Journal of Health Professions Education, 2022
Background. As a core component of any health professions curriculum, basic medical science modules facilitate learning of biology, anatomy, histology and physiology content.
L Keiller, A Alblas, J R Foiret, A V Keiller   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Health literacy disparities in South Korea: insights from a latent profile analysis

BMC Public Health
Background Health literacy has been empirically linked to overall health outcomes. Existing interventions generally employ a variable-centred approach, often neglecting the cumulative impact of various factors and the ways different groups interact with ...
Sunghyun Kim, Suwon Hwang, Junhyup Lee, Mankyu Choi   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Integrating Knowledge Translation: A Swiss Approach to Bridging Research and Health System Improvement

Learning Health Systems
Introduction The Swiss Learning Health System (SLHS), funded from 2017 to 2025, facilitated the movement of research to practice and policy, responding to national calls to enhance health services research and build research scientist capacity.
Natalie Gray Messerli, Sarah Mantwill
doaj   +1 more source

Targeted assessment of prevalence of zero-dose and under-immunised children in Bangladesh

BMJ Global Health
Introduction Gavi, the Vaccine Alliance and the Global Immunisation Agenda 2030 have intensified their emphasis on equity, with the intent of reaching zero-dose (ZD—missing the first dose of pentavalent) and under-immunised (UI—missing the third dose of ...
Christopher Morgan, Nurul Alam, Elizabeth Oliveras, Md. Jasim Uddin, Tabita Jannatul, Gustavo C. Corrêa, Heidi W. Reynolds, Zerin Jannat, Hemel Das, Md Wazed Ali   +9 more
doaj   +1 more source

Local Toxicity of Biocides after Direct and Aerosol Exposure on the Human Skin Epidermis and Airway Tissue Models

Toxics, 2021
Biocides are commonly used as spray- or trigger-type formulations, thus dermal and respiratory exposure to biocide aerosol is unavoidable. However, little is known about the impact of aerosolization on the local toxicity of biocides on the skin or the ...
Nahyun Lee, Dae Yong Jang, Do Hyeon Lee, Haengdueng Jeong, Ki Taek Nam, Dal-Woong Choi, Kyung-Min Lim   +6 more
doaj   +1 more source