Results 81 to 90 of about 6,041,785 (280)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Gondang: Jurnal Seni dan Budaya, 2020 Padhepokan Seni Mangun Dharma is a traditional art studio in Malang Regency. The art taught in this studio is Malang Puppet Mask, kerawitan, dance, pedhdalang, mocopatan.
Gesti Manggarrani Pratiwi +1 more
doaj +1 more source
Learning and Selection Processes
THEORIA, 2010 In this paper I defend a teleological explanation of normativity, i. e., I argue that what an organism (or device) is supposed to do is determined by its etiological function. In particular, I present a teleological account of the normativity that arises in learning processes, and I defend it from some objections.
openaire +5 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Factors causing difficulties in learning vocabulary by the fifth year students of ngringo 02 Elementary School Karanganyar in the Academic Year of 2005/2006� [PDF]
, 2006 This thesis is intended to 1) analyze the process of teaching and learning vocabulary at the fifth year students of Ngringo 02 elementary school, 2) identify difficulties faced by the students in vocabulary learning, 3) identify and formulate factors ...
Musdalifah,
core
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
SOCIOCULTURAL SPHERES OF LIFE OF THE BELARUSIAN LANGUAGE IN THE CONTEXT OF TWO STATE LANGUAGES
Polylinguality and Transcultural Practices, 2017 The Belarusian and Russian languages have equal status in the Republic of Belarus. Both of them are used in the media sphere, education and clerical work.Teaching in the institutions of general and high education is realized according to the equal number
S V Nikolaenko
doaj +1 more source