Results 51 to 60 of about 650,177 (374)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Legal Certainty of Lease Rights for Foreign Citizens of Ownership Land in Indonesia
Batulis Civil Law ReviewIntroduction: In Indonesia, regulations have been issued that guarantee certainty over land in Indonesia, one of which is Law Number 5 of 1960 concerning Basic Agrarian Law, which was subsequently derived using Government Regulation Number 10 of 1961 ...
Yudha Tri Dharma Iswara +2 more
doaj +1 more source
Exploiting Locality in Lease-Based Replicated Transactional Memory via Task Migration [PDF]
International Symposium on Distributed Computing, 2013 We present Lilac-TM, the first locality-aware Distributed Software Transactional Memory (DSTM) implementation. Lilac-TM is a fully decentralized lease-based replicated DSTM. It employs a novel self-optimizing lease circulation scheme based on the idea of
Danny Hendler +5 more
semanticscholar +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Arenda funciară ca mecanism efectiv de reparcelare a terenurilor agricole în Republica Moldova
Agricultural Science, 2011 The article is focused on the investigation of land re-parceling through land lease market development in Moldova. First, it describes land lease market development in Moldova and its impact on land re-parceling. Second, it analyzes strategies adopted by
CIMPOIEŞ Dragoş
doaj
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Active Discriminative Text Representation Learning
, 2016 We propose a new active learning (AL) method for text classification with convolutional neural networks (CNNs). In AL, one selects the instances to be manually labeled with the aim of maximizing model performance with minimal effort.
Lease, Matthew +2 more
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Code4Lib Journal, 2008 It is a pleasure and an honor to be able to introduce this, the second issue of Code4Lib Journal. Code4Lib is much more than a journal. It is a thriving community.
Eric Lease Morgan
doaj