Results 91 to 100 of about 1,437,192 (281)
Least Squares Problems with Absolute Quadratic Constraints
Journal of Applied Mathematics, 2012 This paper analyzes linear least squares problems with absolute quadratic constraints. We develop a generalized theory following Bookstein's conic-fitting and Fitzgibbon's direct ellipse-specific fitting.
R. Schöne, T. Hanning
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Jackknifing estimated weighted least squares [PDF]
Statistical ...
Karremans, P. +2 more
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FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
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Partial Least Squares Regression for Binary Data
MathematicsClassical Partial Least Squares Regression (PLSR) models were developed primarily for continuous data, allowing dimensionality reduction while preserving relationships between predictors and responses. However, their application to binary data is limited.
Laura Vicente-Gonzalez +2 more
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Least-Squares Solution of Linear Differential Equations
Mathematics, 2017 This study shows how to obtain least-squares solutions to initial value problems (IVPs), boundary value problems (BVPs), and multi-value problems (MVPs) for nonhomogeneous linear differential equations (DEs) with nonconstant coefficients of any order ...
Daniele Mortari
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
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Least-Squares Means: The R Package lsmeans
Journal of Statistical Software, 2016 Least-squares means are predictions from a linear model, or averages thereof. They are useful in the analysis of experimental data for summarizing the effects of factors, and for testing linear contrasts among predictions. The lsmeans package (Lenth 2016)
Russell V. Lenth
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FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
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Least Squares for Practitioners [PDF]
Mathematical Problems in Engineering, 2010 In experimental science and engineering, least squares are ubiquitous in analysis and digital data processing applications. Minimizing sums of squares of some quantities can be interpreted in very different ways and confusion can arise in practice, especially concerning the optimality and reliability of the results.
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Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
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