Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
An Experimental Analysis on Scalable Implementations of the Alternating Least Squares Algorithm [PDF]
Annals of computer science and information systems, 2018 Dânia Meira +2 more
doaj +1 more source
A partial least squares analysis of functional status, disability, and quality of life after surgical decompression for degenerative cervical myelopathy. [PDF]
Sci Rep, 2020 Badhiwala JH +8 more
europepmc +1 more source
Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen +10 more
wiley +1 more source
Least Median of Squares Estimation by Optimization Heuristics with an Application to the CAPM and Multi Factor Models [PDF]
For estimating the parameters of models for financial market data, the use of robust techniques is of particular interest. Conditional forecasts, based on the capital asset pricing model, and a factor model are considered.
Chris Sharpe +2 more
core
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Feasibility Analysis of Indoor 3D Localization System with UWB Using Least Squares Trilateration [PDF]
Iranian Journal of Electrical and Electronic EngineeringAccurate 3D Localization is very important for a wide range of applications, such as indoor navigation, industrial robotics, and motion tracking. This research focuses on indoor 3D positioning systems using ultra-wideband (UWB) devices. Two localization
Muhammad Naqib Mohd Shukri +4 more
doaj
Effects of Patient Portal Use on Patient Satisfaction: Survey and Partial Least Squares Analysis.
J Med Internet Res, 2021 Kinney AP, Sankaranarayanan B.
europepmc +1 more source
A least squares approach to Principal Component Analysis for interval valued data [PDF]
Principal Component Analysis (PCA) is a well known technique the aim of which is to synthesize huge amounts of numerical data by means of a low number of unobserved variables, called components.
D'Urso, Pierpaolo, Giordani, Paolo
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source