Results 41 to 50 of about 12,710,147 (277)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Soil compressibility and least limiting water range of a constructed soil under cover crops after coal mining in Southern Brazil

, 2012
The use of cover crops affects the support capacity of soil and least limiting water range to crop growth. The objective of this study was to quantify preconsolidation pressure (sigma(p)), compression index (CI) and least limiting water range (LLWR) of a
Carvalho Miola, Ezequiel Cesar, Timm, Luis Carlos, da Silva, Alvaro Aires, Rodrigues de Lima, Claudia Liane, Pauletto, Eloy Antonio   +4 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

PHYSICAL QUALITY OF SOILS UNDER A CROP-LIVESTOCK-FOREST SYSTEM IN THE CERRADO/AMAZON TRANSITION REGION

Revista Árvore, 2018
Integrated crop-livestock-forest (iCLF) systems have gained prominence in the past decades as an alternative of sustainable land use, particularly in regions in which there is pressure against agricultural expansion in protected ecosystems such as the ...
Guilherme Musse Moreira, Júlio César Lima Neves, Genelício Crusoé Rocha, Ciro Augusto de Souza Magalhães, Austeclinio Lopes Farias Neto, João Luiz Palma Meneguci, Raphael B.A. Fernandes   +6 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Spatial variability of the least limiting water range of soils under a no‑tillage system

, 2016
The objective of this work was to evaluate the regressions that define the least limiting water range limits and the validity of using this indicator considering the spatial variability of crops under a no‑tillage system.
Daubermann, André Guilherme, Graebin, Gilvan Jaciel, Bortolanza, Delcio Rudinei, Klein, Vilson Antonio   +3 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Intervalo hídrico ótimo num nitossolo vermelho distroférrico irrigado Least limiting water range of an irrigated dystroferric red nitosol

Revista Brasileira de Ciência do Solo, 2009
O manejo da irrigação tem-se baseado no controle do potencial da água no solo (Ψ) como fator limitante do crescimento das plantas. Entretanto, outras variáveis podem influenciar a cultura mesmo que o Ψ não seja limitante.
Everton Blainski, Antonio Carlos Andrade Gonçalves, Cássio Antonio Tormena, Marcos Vinicius Folegatti, Rachel Muylaert Locks Guimarães   +4 more
doaj   +1 more source

Structural changes in latosols of the cerrado region: I - relationships between soil physical properties and least limiting water range

Revista Brasileira de Ciência do Solo, 2011
The agricultural potential of Latosols of the Brazilian Cerrado region is high, but when intensively cultivated under inappropriate management systems, the porosity can be seriously reduced, leading to rapid soil degradation.
Eduardo da Costa Severiano, Geraldo César de Oliveira, Moacir de Souza Dias Júnior, Katia Aparecida de Pinho Costa, Fabiano Guimarães Silva, Silvio Marcos Ferreira Filho   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source