Results 151 to 160 of about 7,450,685 (340)
Impact of Narrow Lanes on Arterial Road Vehicle Crashes: A Machine Learning Approach [PDF]
In this paper we adopted state-of-the-art machine learning algorithms, namely: random forest (RF) and least squares boosting, to model crash data and identify the optimum model to study the impact of narrow lanes on the safety of arterial roads. Using a ten-year crash dataset in four cities in Nebraska, two machine learning models were assessed based ...
arxiv
Handedness and Depression - Evidence from a Large Population Survey [PDF]
This paper uses a new large population survey from twelve European countries to measure the association between handedness and depression. It is found that that depressive symptoms are significantly higher amongst left- handed men.
Kevin Denny
core
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Background:. Residents seek inclusive training environments that prioritize diversity. To evaluate programs that focus on these elements, websites have become essential for applicants but often lack in diversity, equity, and inclusion (DEI) content. Thus,
Dylan G. Choi, BS+5 more
doaj +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Hand grip strength in dentists: A comprehensive evaluation of head position, dominance, age, and sex
This study aimed to identify the effect of different head positions on hand grip strength (HGS) on account of hand dominance, age, and sex in dentists.
Hayam Mahmoud+9 more
doaj +1 more source