Results 41 to 50 of about 2,015,824 (285)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Least-Squares Covariance Matrix Adjustment [PDF]
, 2005 We consider the problem of finding the smallest adjustment to a given symmetric $n \times n$ matrix, as measured by the Euclidean or Frobenius norm, so that it satisfies some given linear equalities and inequalities, and in addition is positive ...
Boyd, Stephen, Xiao, Lin
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Efficient least-squares basket-weaving
, 2012 We report on a novel method to solve the basket-weaving problem. Basket-weaving is a technique that is used to remove scan-line patterns from single-dish radio maps. The new approach applies linear least-squares and works on gridded maps from arbitrarily
Flöer, L., Kraus, A., Winkel, B.
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Coupled Least Squares Support Vector Ensemble Machines
Information, 2019 The least squares support vector method is a popular data-driven modeling method which shows better performance and has been successfully applied in a wide range of applications.
Dickson Keddy Wornyo, Xiang-Jun Shen
doaj +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Marginal Screening for Partial Least Squares Regression
IEEE Access, 2017 Partial least squares (PLS) regression is a versatile modeling approach for high-dimensional data analysis. Recently, PLS-based variable selection has attracted great attention due to high-throughput data reduction and modeling interpretability.
Naifei Zhao, Qingsong Xu, Hong Wang
doaj +1 more source
New Developments in Sparse PLS Regression
Frontiers in Applied Mathematics and Statistics, 2021 Methods based on partial least squares (PLS) regression, which has recently gained much attention in the analysis of high-dimensional genomic datasets, have been developed since the early 2000s for performing variable selection.
Jérémy Magnanensi +6 more
doaj +1 more source