Results 51 to 60 of about 556,024 (263)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Marginal Screening for Partial Least Squares Regression
IEEE Access, 2017 Partial least squares (PLS) regression is a versatile modeling approach for high-dimensional data analysis. Recently, PLS-based variable selection has attracted great attention due to high-throughput data reduction and modeling interpretability.
Naifei Zhao, Qingsong Xu, Hong Wang
doaj +1 more source
New Developments in Sparse PLS Regression
Frontiers in Applied Mathematics and Statistics, 2021 Methods based on partial least squares (PLS) regression, which has recently gained much attention in the analysis of high-dimensional genomic datasets, have been developed since the early 2000s for performing variable selection.
Jérémy Magnanensi +6 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
LEAST SQUARES MULTI-WINDOW EVOLUTIONARY SPECTRAL ESTIMATION
Electrica, 2003 We present a multi-window method for obtaining the time-frequency spectrum of non-stationary signals such as speech and music. This method is based on optimal combination of evolutionary spectra that are calculated by using multi-window Gabor expansion ...
Mahmut YALÇIN, Aydın AKAN
doaj +2 more sources
A novel interpretation of least squares solution
International Journal of Mathematics and Mathematical Sciences, 1992 We show that the well-known least squares (LS) solution of an overdetermined system of linear equations is a convex combination of all the non-trivial solutions weighed by the squares of the corresponding denominator determinants of the Cramer's rule ...
Jack-Kang Chan
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Least Squares Consensus for Matching Local Features
Information, 2019 This paper presents a new approach to estimate the consensus in a data set. Under the framework of RANSAC, the perturbation on data has not been considered sufficiently.
Qingming Zhang, Buhai Shi, Haibo Xu
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Least Squares Optimization: From Theory to Practice
Robotics, 2020 Nowadays, Nonlinear Least-Squares embodies the foundation of many Robotics and Computer Vision systems. The research community deeply investigated this topic in the last few years, and this resulted in the development of several open-source solvers to ...
Giorgio Grisetti +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source