Results 71 to 80 of about 2,031,080 (289)

Alternating least squares as moving subspace correction

open access: yes, 2018
In this note we take a new look at the local convergence of alternating optimization methods for low-rank matrices and tensors. Our abstract interpretation as sequential optimization on moving subspaces yields insightful reformulations of some known ...
Oseledets, Ivan   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Penerapan Partial Least Squares Pada Data Gingerol

open access: yesComTech, 2010
Multivariate calibration model aims to predict the expensive measures obtained by using the measures of a cheap and easy. There are several problems that often occur in the model calibration, among others, and multikolinear. To overcome these problems we
Margaretha Ohyver
doaj   +1 more source

A note on sparse least-squares regression [PDF]

open access: yes, 2013
We compute a \emph{sparse} solution to the classical least-squares problem $\min_x||A x -b||,$ where $A$ is an arbitrary matrix. We describe a novel algorithm for this sparse least-squares problem.
Boutsidis, Christos   +1 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Monotonic Properties of the Least Squares Mean

open access: yes, 2010
We settle an open problem of several years standing by showing that the least-squares mean for positive definite matrices is monotone for the usual (Loewner) order.
Lawson, Jimmie, Lim, Yongdo
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Properties of the total least squares estimation

open access: yesGeodesy and Geodynamics, 2012
Through theoretical derivation, some properties of the total least squares estimation are found. The total least squares estimation is the linear transformation of the least squares estimation, and the total least squares estimation is unbiased.
Wang Leyang
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Forensic Speaker Verification Using Ordinary Least Squares

open access: yesSensors, 2019
In Brazil, the recognition of speakers for forensic purposes still relies on a subjectivity-based decision-making process through a results analysis of untrustworthy techniques.
Thyago J. Machado   +2 more
doaj   +1 more source

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