Results 51 to 60 of about 2,015,824 (285)

Alternating least squares as moving subspace correction

open access: yes, 2018
In this note we take a new look at the local convergence of alternating optimization methods for low-rank matrices and tensors. Our abstract interpretation as sequential optimization on moving subspaces yields insightful reformulations of some known ...
Oseledets, Ivan   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

A novel interpretation of least squares solution

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1992
We show that the well-known least squares (LS) solution of an overdetermined system of linear equations is a convex combination of all the non-trivial solutions weighed by the squares of the corresponding denominator determinants of the Cramer's rule ...
Jack-Kang Chan
doaj   +1 more source

Least Squares Consensus for Matching Local Features

open access: yesInformation, 2019
This paper presents a new approach to estimate the consensus in a data set. Under the framework of RANSAC, the perturbation on data has not been considered sufficiently.
Qingming Zhang, Buhai Shi, Haibo Xu
doaj   +1 more source

Local Regularization Assisted Orthogonal Least Squares Regression

open access: yes, 2006
A locally regularized orthogonal least squares (LROLS) algorithm is proposed for constructing parsimonious or sparse regression models that generalize well.
Chen, S.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Least Squares Ranking on Graphs [PDF]

open access: yes, 2011
Given a set of alternatives to be ranked, and some pairwise comparison data, ranking is a least squares computation on a graph. The vertices are the alternatives, and the edge values comprise the comparison data.
Hirani, Anil N.   +2 more
core  

Implicitly Constrained Semi-Supervised Least Squares Classification

open access: yes, 2015
We introduce a novel semi-supervised version of the least squares classifier. This implicitly constrained least squares (ICLS) classifier minimizes the squared loss on the labeled data among the set of parameters implied by all possible labelings of the ...
B Widrow   +16 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Least Squares Optimization: From Theory to Practice

open access: yesRobotics, 2020
Nowadays, Nonlinear Least-Squares embodies the foundation of many Robotics and Computer Vision systems. The research community deeply investigated this topic in the last few years, and this resulted in the development of several open-source solvers to ...
Giorgio Grisetti   +5 more
doaj   +1 more source

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