Results 71 to 80 of about 2,015,824 (285)

Forensic Speaker Verification Using Ordinary Least Squares

open access: yesSensors, 2019
In Brazil, the recognition of speakers for forensic purposes still relies on a subjectivity-based decision-making process through a results analysis of untrustworthy techniques.
Thyago J. Machado   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Least Mean Squares and Recursive Least Squares Algorithms for Total Harmonic Distortion Reduction Using Shunt Active Power Filter Control

open access: yesEnergies, 2019
This paper deals with the use of least mean squares (LMS, NLMS) and recursive least squares (RLS) algorithms for total harmonic distortion (THD) reduction using shunt active power filter (SAPF) control.
Radek Martinek   +4 more
doaj   +1 more source

A new distribution for robust least squares [PDF]

open access: yes, 2014
A new distribution is introduced, which we call the twin-t distribution. This distribution is heavy-tailed like the t distribution, but closer to normality in the central part of the curve. Its properties are described, e.g.
Baker, Rose, Jackson, Dan
core  

Analysis of moving least squares approximation revisited

open access: yes, 2015
In this article the error estimation of the moving least squares approximation is provided for functions in fractional order Sobolev spaces. The analysis presented in this paper extends the previous estimations and explains some unnoticed mathematical ...
Mirzaei, Davoud
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Sparse least trimmed squares regression. [PDF]

open access: yes
Sparse model estimation is a topic of high importance in modern data analysis due to the increasing availability of data sets with a large number of variables. Another common problem in applied statistics is the presence of outliers in the data.
Alfons, Andreas   +2 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Comparison of straight line curve fit approaches for determining parameter variances and covariances

open access: yesInternational Journal of Metrology and Quality Engineering, 2020
Pressure balances are known to have a linear straight line equation of the form y = ax + b that relates the applied pressure x to the effective area y, and recent work has investigated the use of Ordinary Least Squares (OLS), Weighted Least Squares (WLS),
Ramnath Vishal
doaj   +1 more source

Home - About - Disclaimer - Privacy