Results 81 to 90 of about 2,028,925 (265)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Decision-Directed Recursive Least Squares MIMO Channels Tracking
EURASIP Journal on Wireless Communications and Networking, 2006 A new approach for joint data estimation and channel tracking for multiple-input multiple-output (MIMO) channels is proposed based on the decision-directed recursive least squares (DD-RLS) algorithm.
Karami Ebrahim, Shiva Mohsen
doaj +2 more sources
Least Squares Ranking on Graphs [PDF]
, 2011 Given a set of alternatives to be ranked, and some pairwise comparison data, ranking is a least squares computation on a graph. The vertices are the alternatives, and the edge values comprise the comparison data.
Hirani, Anil N. +2 more
core
Properties of the total least squares estimation
Geodesy and Geodynamics, 2012 Through theoretical derivation, some properties of the total least squares estimation are found. The total least squares estimation is the linear transformation of the least squares estimation, and the total least squares estimation is unbiased.
Wang Leyang
doaj +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Forensic Speaker Verification Using Ordinary Least Squares
Sensors, 2019 In Brazil, the recognition of speakers for forensic purposes still relies on a subjectivity-based decision-making process through a results analysis of untrustworthy techniques.
Thyago J. Machado +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Sequential Least-Squares Using Orthogonal Transformations [PDF]
Square root information estimation, starting from its beginnings in least-squares parameter estimation, is considered. Special attention is devoted to discussions of sensitivity and perturbation matrices, computed solutions and their formal statistics ...
Bierman, G. J.
core +1 more source
A robust partial least squares method with applications [PDF]
, 2007 Partial least squares regression (PLS) is a linear regression technique developed to relate many regressors to one or several response variables. Robust methods are introduced to reduce or remove the effect of outlying data points.
González, Javier +2 more
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source