Results 31 to 40 of about 12,224 (267)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Comparitive Study Between Two Ways Least Squares and Adaptive Regression In Regression linear model [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2007
In this research, we use the ( ) and ( ) two criterions to compare between the estimators of Adaptive Regression model and the estimators of Ordinary and General Least Squares. We found that, Adaptive Regression estimators are more accurate and efficient
doaj   +1 more source

Least-Squares Estimators of Drift Parameter for Discretely Observed Fractional Ornstein–Uhlenbeck Processes

open access: yesMathematics, 2020
We introduce three new estimators of the drift parameter of a fractional Ornstein–Uhlenbeck process. These estimators are based on modifications of the least-squares procedure utilizing the explicit formula for the process and covariance structure of a ...
Pavel Kříž, Leszek Szała
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Predictive efficiency of ridge regression estimator [PDF]

open access: yesYugoslav Journal of Operations Research, 2017
In this article we have considered the problem of prediction within and outside the sample for actual and average values of the study variables in case of ordinary least squares and ridge regression estimators.
Tiwari Manoj, Sharma Amit
doaj   +1 more source

Robust-M new two-parameter estimator for linear regression models: Simulations and applications

open access: yesAfrican Scientific Reports, 2023
In the presence of multicollinearity and outliers, the ordinary least squares estimator remains inconsistent and unreliable. Several estimators have been proposed that can co-handle the problems of multicollinearity and outliers simultaneously.
Taiwo Joel Adejumo   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Comparison Study Between Two Ways Least Squares and Adaptive Regression In Regression linear model [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2007
In this research, we use on ( ) and ( ) two criterions to compare between the estimators of Adaptive Regression model and the estimators of Ordinary and General Least Squares, we found that, Adaptive Regression estimator is the best by comparing with ...
doaj   +1 more source

Kibria-Lukman Estimator for General Linear Regression Model with AR(2) Errors: A Comparative Study with Monte Carlo Simulation

open access: yesJournal of New Theory, 2022
The sensitivity of the least-squares estimation in a regression model is impacted by multicollinearity and autocorrelation problems. To deal with the multicollinearity, Ridge, Liu, and Ridge-type biased estimators have been presented in the statistical ...
Tuğba Söküt Açar
doaj   +1 more source

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