Results 151 to 160 of about 2,627,626 (274)

Beyond Activity: The Unified Framework of the Sabatier Principle to Guide Rational Design of Durable and Active Electrocatalysts

open access: yesCarbon Energy, EarlyView.
In this review, a unified framework of the Sabatier principle is applied to a diverse range of catalytic and electrocatalytic systems for advanced clean energy technologies, with a particular focus on the oxygen reduction reaction (ORR). This approach will guide the design and development of highly active and stable catalysts for fuel cells ...
Wanying Zhang   +6 more
wiley   +1 more source

Dynamic survival risk prediction with time‐varying high‐dimensional images

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Integrating longitudinal data with survival models is a prevalent strategy for dynamic survival risk prediction while accounting for subjects' longitudinally observed variables. However, existing methods primarily focus on scalar longitudinal data and seldom tackle the complexities associated with high‐dimensional longitudinal imaging data ...
Bingfan Liu   +7 more
wiley   +1 more source

Lasso for hierarchical polynomial models

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract The divisibility conditions implicit in a polynomial hierarchy suggest parameter constraints in regression. With this idea, we establish strong and weak hierarchies for both the lasso and relaxed lasso. Our proposal extends prior work on hierarchical lasso, which was mainly concerned with models of degree 2.
H. Maruri‐Aguilar, S. Lunagómez
wiley   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas   +5 more
wiley   +1 more source

A robust partial least squares method with applications [PDF]

open access: yes
Partial least squares regression (PLS) is a linear regression technique developed to relate many regressors to one or several response variables. Robust methods are introduced to reduce or remove the effect of outlying data points.
Javier Gonzalez   +2 more
core  

From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley   +1 more source

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