Results 161 to 170 of about 2,627,626 (274)

A Robust Computational Workflow Utilizing Generalized Least Squares (GLS) and Generalized Estimating Equations (GEE‐GLM) for Longitudinal Flow Cytometry Maturation Data Analysis

open access: yesCytometry Part A, EarlyView.
ABSTRACT Routinely used statistical hypothesis tests are often inadequate for longitudinal flow cytometry data, necessitating more sophisticated modeling approaches. Analyzing dynamic biomarker expression across hematopoietic maturation presents several analytical challenges, notably nonlinearity, serial correlation between subsequent stages, and ...
Sixuan Joanna Wang   +8 more
wiley   +1 more source

Responses of Antarctic seabird populations to past climate change

open access: yesEcography, EarlyView.
Higher‐order predators such as Antarctic seabirds serve as ecological indicators of environmental change and provide a crucial trophic link between marine and terrestrial ecosystems. Despite their prevalence and significance in the Antarctic ecosystem, there is a lack of understanding of the impacts of major regime shifts in paleoclimate on flighted ...
Elize Y. X. Ng   +6 more
wiley   +1 more source

Fast algorithm for sparse least trimmed squares via trimmed-regularized reformulation

open access: yes
The least trimmed squares (LTS) is a reasonable formulation of robust regression whereas it suffers from high computational cost due to the nonconvexity and nonsmoothness of its objective function. The most frequently used FAST-LTS algorithm is particularly slow when a sparsity-inducing penalty such as the $\ell_1$ norm is added.
openaire   +2 more sources

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen   +7 more
wiley   +1 more source

Regioselective Oxidative Oligomerization of 2‐Tert‐Butylpyrene Toward Structurally Defined Oligomers and Their Application in Organic Light‐Emitting Diodes

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Treatment of 2‐tert‐butylpyrene with Cu2+ afforded structurally well‐defined pyrene oligomers, up to the 13‐mer. Single‐crystal X‐ray diffraction, spectroscopic analyses, and computational studies were conducted to evaluate the properties of the resulting oligopyrenes.
Md Jadu Mia   +14 more
wiley   +1 more source

Transcriptional signatures of cortical morphometric variability in temporal lobe epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Widespread cognitive deficits in temporal lobe epilepsy (TLE) are associated with macroscale brain structural changes. However, the correlation between the changes in the cortical morphological similarity of the TLE and gene expression remains unclear.
Yaping Dong   +5 more
wiley   +1 more source

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