Post-LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor. [PDF]
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
King SM.
europepmc +2 more sources
How actors move from primary agency to institutional agency: A conceptual framework and empirical application [PDF]
This article contributes to the understanding of actors and agency in the theorization of institutional work. We analyse institutional work as a specific kind of social action that involves exercising institutional agency (with an articulate awareness of
Maier, Florentine, Simsa, Ruth
core +1 more source
Paraneoplastic hypoglycaemia secondary to IGF-2 secretion from a metastatic gastrointestinal stromal tumour [PDF]
We report the case of a 79-year-old male with previous history of non-Hodgkin's lymphoma in remission, who presented acutely to the Accident and Emergency department with recurrent episodes of hypoglycaemia.
Dimitriadis, Georgios K. +9 more
core +1 more source
Targeting the Central Pocket of the Pseudomonas aeruginosa Lectin LecA [PDF]
AbstractPseudomonas aeruginosa is an opportunistic ESKAPE pathogen that produces two lectins, LecA and LecB, as part of its large arsenal of virulence factors. Both carbohydrate‐binding proteins are central to the initial and later persistent infection processes, i. e. bacterial adhesion and biofilm formation.
Eike Siebs +9 more
openaire +6 more sources
Protein-observed 19F NMR of LecA from Pseudomonas aeruginosa [PDF]
Abstract The carbohydrate-binding protein LecA (PA-IL) from Pseudomonas aeruginosa plays an important role in the formation of biofilms in chronic infections. Development of inhibitors to disrupt LecA-mediated biofilms is desired but it is limited to carbohydrate-based ligands.
Elena Shanina +6 more
openaire +4 more sources
Evolutionary cell biology: Functional insight from “Endless forms most beautiful” [PDF]
In animal and fungal model organisms, the complexities of cell biology have been analyzed in exquisite detail and much is known about how these organisms function at the cellular level.
Dacks, Joel B. +4 more
core +1 more source
Groundwater samples contaminated with potentially toxic elements (PTE), including metals and nitrate ions, were collected at a depth of 8–10 m from the Siberian Chemical Plant multicomponent waste storage.
Nadezhda Popova +7 more
doaj +1 more source
In addition to combating vector‐borne diseases, studying the adaptation of mosquitoes to insecticides provides a remarkable example of evolution‐in‐action driving the selection of complex phenotypes.
Julien Cattel +10 more
doaj +1 more source
Development of Sustainable Precast Concrete Sandwich Wall Panels using artificial aggregates and mineral admixture [PDF]
This study investigates the development of sustainable precast concrete sandwich wall panels using alternative materials. This study explores the partial replacement of natural aggregates with Lightweight Expanded Clay Aggregate (LECA) and marble waste ...
Kumar Pushpender +4 more
doaj +1 more source
Standard operating procedures (SOP) in experimental stroke research: SOP for middle cerebral artery occlusion in the mouse [PDF]
Recently, systematic reviews have found quantitative evidence that low study quality may have introduced a bias into preclinical stroke research. Monitoring, auditing, and standard operating procedures (SOPs) are already key elements of quality control ...
Members of the MCAO-SOP Group +1 more
core +2 more sources

