Results 1 to 10 of about 23,814 (213)
Discovery of fibrillar adhesins across bacterial species [PDF]
BMC Genomics, 2021 Background Fibrillar adhesins are long multidomain proteins that form filamentous structures at the cell surface of bacteria. They are an important yet understudied class of proteins composed of adhesive and stalk domains that mediate interactions of ...
Vivian Monzon +2 more
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Platelets, Bacterial Adhesins and the Pneumococcus
Cells, 2022 Systemic infections with pathogenic or facultative pathogenic bacteria are associated with activation and aggregation of platelets leading to thrombocytopenia and activation of the clotting system.
Kristin Jahn +4 more
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Binding Strength of Gram-Positive Bacterial Adhesins [PDF]
Frontiers in Microbiology, 2020 Bacterial pathogens are equipped with specialized surface-exposed proteins that bind strongly to ligands on host tissues and biomaterials. These adhesins play critical roles during infection, especially during the early step of adhesion where the cells ...
Yves F. Dufrêne, Albertus Viljoen
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Stopping Tuberculosis at the Gate: The Role of M. tuberculosis Adhesins in Infection and Intervention [PDF]
VaccinesThe global burden of tuberculosis (TB), exacerbated by the rise of drug-resistant Mycobacterium tuberculosis (M. tuberculosis), underscores the need for alternative intervention strategies. One promising approach is to block the infection at its earliest
Haoyan Yang +7 more
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FaaPred: a SVM-based prediction method for fungal adhesins and adhesin-like proteins. [PDF]
PLoS ONE, 2010 Adhesion constitutes one of the initial stages of infection in microbial diseases and is mediated by adhesins. Hence, identification and comprehensive knowledge of adhesins and adhesin-like proteins is essential to understand adhesin mediated ...
Jayashree Ramana, Dinesh Gupta
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Sticking to the Subject: Multifunctionality in Microbial Adhesins
Journal of Fungi, 2023 Bacterial and fungal adhesins mediate microbial aggregation, biofilm formation, and adhesion to host. We divide these proteins into two major classes: professional adhesins and moonlighting adhesins that have a non-adhesive activity that is ...
Peter N. Lipke, Peleg Ragonis-Bachar
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Microbiology Spectrum, 2023 Bacteria can rapidly tune their physiology and metabolism to adapt to environmental fluctuations. In particular, they can adapt their lifestyle to the close proximity of other bacteria or the presence of different surfaces.
Yankel Chekli +5 more
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Adhesins in the virulence of opportunistic fungal pathogens of human
Mycology, 2021 Aspergillosis, candidiasis, and cryptococcosis are the most common cause of mycoses-related disease and death among immune-compromised patients. Adhesins are cell-surface exposed proteins or glycoproteins of pathogens that bind to the extracellular ...
Amrita Kumari +7 more
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mBio, 2021 Pathogen attachment to host tissue is critical in the progress of many infections. Bacteria use adhesion in vivo to stabilize colonization and subsequently regulate the deployment of contact-dependent virulence traits.
Xavier Pierrat +3 more
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Evolution of host-microbe cell adherence by receptor domain shuffling
eLife, 2022 Stable adherence to epithelial surfaces is required for colonization by diverse host-associated microbes. Successful attachment of pathogenic microbes to host cells via adhesin molecules is also the first step in many devastating infections.
EmilyClare P Baker +6 more
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