Results 31 to 40 of about 23,814 (213)
CEACAM1 recognition by bacterial pathogens is species-specific
BMC Microbiology, 2010 Background Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), an immunoglobulin (Ig)-related glycoprotein, serves as cellular receptor for a variety of Gram-negative bacterial pathogens associated with the human mucosa.
Kammerer Robert +4 more
doaj +1 more source
The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion
mBio, 2021 Bacteria can exploit membrane receptor integrins for cellular invasion, either by direct binding of bacterial adhesins or utilizing extracellular matrix components.
Xinyue Li +4 more
doaj +1 more source
How bacteria hack the matrix and dodge the bullets of immunity
European Respiratory Review, 2018 Haemophilus influenzae, Moraxella catarrhalis and Pseudomonas aeruginosa are common Gram-negative pathogens associated with an array of pulmonary diseases. All three species have multiple adhesins in their outer membrane, i.e.
Magnus Paulsson, Kristian Riesbeck
doaj +1 more source
Advanced Science, EarlyView.Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao +9 more
wiley +1 more source
An internal thioester in a pathogen surface protein mediates covalent host binding
eLife, 2015 To cause disease and persist in a host, pathogenic and commensal microbes must adhere to tissues. Colonization and infection depend on specific molecular interactions at the host-microbe interface that involve microbial surface proteins, or adhesins.
Miriam Walden +14 more
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Structure and Conservation of Amyloid Spines From the Candida albicans Als5 Adhesin
Frontiers in Molecular Biosciences, 2022 Candida Als family adhesins mediate adhesion to biological and abiotic substrates, as well as fungal cell aggregation, fungal-bacterial co-aggregation and biofilm formation.
Nimrod Golan +4 more
doaj +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
mBio, 2016 The first step in the infection of humans by microbial pathogens is their adherence to host tissue cells, which is frequently based on the binding of carbohydrate-binding proteins (lectin-like adhesins) to human cell receptors that expose glycans.
Francesco S. Ielasi +6 more
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Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity
Advanced Science, EarlyView.Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai +7 more
wiley +1 more source
Inhibitory effect of natural flavone luteolin on Streptococcus mutans biofilm formation
Microbiology Spectrum, 2023 Streptococcus mutans is one of the key pathogens responsible for dental caries, which is known to be one of the most prevalent biofilm-associated diseases worldwide. S.
Lucille Rudin +5 more
doaj +1 more source