Results 21 to 30 of about 23,814 (213)

Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation

open access: yesmBio, 2021
Bacterial adhesins are key virulence factors that are essential for the pathogen-host interaction and biofilm formation that cause most infections. Many of the adhesin-driven cell-cell interactions are mediated by lectins.
Shuaiqi Guo   +7 more
doaj   +1 more source

Adhesins and host serum factors drive Yop translocation by yersinia into professional phagocytes during animal infection. [PDF]

open access: yesPLoS Pathogens, 2013
Yersinia delivers Yops into numerous types of cultured cells, but predominantly into professional phagocytes and B cells during animal infection. The basis for this cellular tropism during animal infection is not understood.
Francisco J Maldonado-Arocho   +4 more
doaj   +1 more source

Adhesive polypeptides of Staphylococcus aureus identified using a novel secretion library technique in Escherichia coli

open access: yesBMC Microbiology, 2011
Background Bacterial adhesive proteins, called adhesins, are frequently the decisive factor in initiation of a bacterial infection. Characterization of such molecules is crucial for the understanding of bacterial pathogenesis, design of vaccines and ...
Holm Liisa   +3 more
doaj   +1 more source

Rapid Aggregation of Staphylococcus aureus in Synovial Fluid Is Influenced by Synovial Fluid Concentration, Viscosity, and Fluid Dynamics, with Evidence of Polymer Bridging

open access: yesmBio, 2022
Early bacterial survival in the postsurgical joint is still a mystery. Recently, synovial fluid-induced aggregation was proposed as a potential mechanism of bacterial protection upon entry into the joint. As synovial fluid is secreted back into the joint
Amelia Staats   +6 more
doaj   +1 more source

Evaluation of cell binding activities of Leptospira ECM adhesins. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
Pathogenic spirochetes of the genus Leptospira are the causative agents of leptospirosis, a zoonotic infection that occurs globally. The bacteria colonize the renal proximal tubules of many animals and are shed in the urine.
Gregory T Robbins   +5 more
doaj   +1 more source

The BtaF trimeric autotransporter of Brucella suis is involved in attachment to various surfaces, resistance to serum and virulence. [PDF]

open access: yesPLoS ONE, 2013
The adhesion of bacterial pathogens to host cells is an event that determines infection, and ultimately invasion and intracellular multiplication. Several evidences have recently shown that this rule is also truth for the intracellular pathogen Brucella.
Verónica Ruiz-Ranwez   +5 more
doaj   +1 more source

Adhesion of Helicobacter Species to the Human Gastric Mucosa: A Deep Look Into Glycans Role

open access: yesFrontiers in Molecular Biosciences, 2021
Helicobacter species infections may be associated with the development of gastric disorders, such as gastritis, peptic ulcers, intestinal metaplasia, dysplasia and gastric carcinoma.
Rita Matos   +14 more
doaj   +1 more source

Catch-bond mechanism of the bacterial adhesin FimH [PDF]

open access: yesNature Communications, 2016
AbstractLigand–receptor interactions that are reinforced by mechanical stress, so-called catch-bonds, play a major role in cell–cell adhesion. They critically contribute to widespread urinary tract infections by pathogenic Escherichia coli strains. These pathogens attach to host epithelia via the adhesin FimH, a two-domain protein at the tip of type I ...
Sauer, Maximilian M.   +9 more
openaire   +6 more sources

Structural biology of gram‐positive bacterial adhesins [PDF]

open access: yesProtein Science, 2011
AbstractThe structural biology of Gram‐positive cell surface adhesins is an emerging field of research, whereas Gram‐negative pilus assembly and anchoring have been extensively investigated and are well understood. Gram‐positive surface proteins known as MSCRAMMs (microbial surface components recognizing adhesive matrix molecules) and individual ...
Krishnan, Vengadesan   +1 more
openaire   +2 more sources

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra   +3 more
wiley   +1 more source

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