Results 21 to 30 of about 847,397 (199)

Role of Hydration in Collagen Recognition by Bacterial Adhesins [PDF]

open access: yesBiophysical Journal, 2011
Protein-protein recognition regulates the vast majority of physiological or pathological processes. We investigated the role of hydration in collagen recognition by bacterial adhesin CNA by means of first principle molecular-dynamics samplings. Our characterization of the hydration properties of the isolated partners highlights dewetting-prone areas on
Vitagliano L, Berisio R, De Simone A
openaire   +4 more sources

Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. [PDF]

open access: yesPLoS ONE, 2013
Pathogenic bacteria interacting with eukaryotic host express adhesins on their surface. These adhesins aid in bacterial attachment to the host cell receptors during colonization.
Sanjiv Kumar   +4 more
doaj   +1 more source

Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation

open access: yesmBio, 2021
Bacterial adhesins are key virulence factors that are essential for the pathogen-host interaction and biofilm formation that cause most infections. Many of the adhesin-driven cell-cell interactions are mediated by lectins.
Shuaiqi Guo   +7 more
doaj   +1 more source

Adhesins and host serum factors drive Yop translocation by yersinia into professional phagocytes during animal infection. [PDF]

open access: yesPLoS Pathogens, 2013
Yersinia delivers Yops into numerous types of cultured cells, but predominantly into professional phagocytes and B cells during animal infection. The basis for this cellular tropism during animal infection is not understood.
Francisco J Maldonado-Arocho   +4 more
doaj   +1 more source

Engineering Mechanosensitive Multivalent Receptor–Ligand Interactions: Why the Nanolinker Regions of Bacterial Adhesins Matter

open access: yes, 2016
Inspired by bacterial adhesins, we present a promising strategy of how to engineer peptides to probe various mechanical strains of extracellular matrix fibers.
Samuel Hertig (2036236)   +2 more
core   +3 more sources

Adhesive polypeptides of Staphylococcus aureus identified using a novel secretion library technique in Escherichia coli

open access: yesBMC Microbiology, 2011
Background Bacterial adhesive proteins, called adhesins, are frequently the decisive factor in initiation of a bacterial infection. Characterization of such molecules is crucial for the understanding of bacterial pathogenesis, design of vaccines and ...
Holm Liisa   +3 more
doaj   +1 more source

Rapid Aggregation of Staphylococcus aureus in Synovial Fluid Is Influenced by Synovial Fluid Concentration, Viscosity, and Fluid Dynamics, with Evidence of Polymer Bridging

open access: yesmBio, 2022
Early bacterial survival in the postsurgical joint is still a mystery. Recently, synovial fluid-induced aggregation was proposed as a potential mechanism of bacterial protection upon entry into the joint. As synovial fluid is secreted back into the joint
Amelia Staats   +6 more
doaj   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra   +3 more
wiley   +1 more source

Evaluation of cell binding activities of Leptospira ECM adhesins. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
Pathogenic spirochetes of the genus Leptospira are the causative agents of leptospirosis, a zoonotic infection that occurs globally. The bacteria colonize the renal proximal tubules of many animals and are shed in the urine.
Gregory T Robbins   +5 more
doaj   +1 more source

The BtaF trimeric autotransporter of Brucella suis is involved in attachment to various surfaces, resistance to serum and virulence. [PDF]

open access: yesPLoS ONE, 2013
The adhesion of bacterial pathogens to host cells is an event that determines infection, and ultimately invasion and intracellular multiplication. Several evidences have recently shown that this rule is also truth for the intracellular pathogen Brucella.
Verónica Ruiz-Ranwez   +5 more
doaj   +1 more source

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