Results 11 to 20 of about 23,814 (213)

Role of Hydration in Collagen Recognition by Bacterial Adhesins [PDF]

open access: yesBiophysical Journal, 2011
Protein-protein recognition regulates the vast majority of physiological or pathological processes. We investigated the role of hydration in collagen recognition by bacterial adhesin CNA by means of first principle molecular-dynamics samplings. Our characterization of the hydration properties of the isolated partners highlights dewetting-prone areas on
Vitagliano L, Berisio R, De Simone A
openaire   +4 more sources

Vibrio cholerae biofilms use modular adhesins with glycan-targeting and nonspecific surface binding domains for colonization

open access: yesNature Communications, 2023
Bacterial biofilms are formed on environmental surfaces and host tissues, and facilitate host colonization and antibiotic resistance by human pathogens.
Xin Huang   +17 more
doaj   +1 more source

Helicobacter pylori employs a general protein glycosylation system for the modification of outer membrane adhesins

open access: yesGut Microbes, 2022
Helicobacter pylori infection is associated with the development of several gastric diseases including gastric cancer. To reach a long-term colonization in the host stomach, H.
Kai-Wen Teng   +12 more
doaj   +1 more source

Identification of cell-binding adhesins of Leptospira interrogans. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
Leptospirosis is a globally distributed bacterial infectious disease caused by pathogenic members of the genus Leptospira. Infection can lead to illness ranging from mild and non-specific to severe, with jaundice, kidney and liver dysfunction, and ...
Karen V Evangelista   +5 more
doaj   +1 more source

Yersinia pseudotuberculosis-derived adhesins

open access: yesИнфекция и иммунитет, 2019
Around fifteen surface components referred to adhesins have been identified in Yersinia pseudotuberculosis combining primarily microbiological, molecular and genetic, as well as immunochemical and biophysical methods. Y.
A. A. Byvalov, I. V. Konyshev
doaj   +1 more source

Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. [PDF]

open access: yesPLoS ONE, 2013
Pathogenic bacteria interacting with eukaryotic host express adhesins on their surface. These adhesins aid in bacterial attachment to the host cell receptors during colonization.
Sanjiv Kumar   +4 more
doaj   +1 more source

Bacterial adhesins: function and structure

open access: yesInternational Journal of Medical Microbiology, 2000
Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens. The fundamental processes that determine bacterial attachment to host tissue surfaces are mediated by microbial adhesins. Host specificity and tissue tropism are characteristics exhibited by different bacteria and are determined (at least in part) by ...
Klemm, Per, Schembri, Mark A.
openaire   +4 more sources

Bacterial Adhesins in Host-Microbe Interactions [PDF]

open access: yesCell Host & Microbe, 2009
Most commensal and pathogenic bacteria interacting with eukaryotic hosts express adhesive molecules on their surfaces that promote interaction with host cell receptors or with soluble macromolecules. Even though bacterial attachment to epithelial cells may be beneficial for bacterial colonization, adhesion may come at a cost because bacterial ...
Kline, Kimberly A.   +4 more
openaire   +2 more sources

Capsule Shields the Function of Short Bacterial Adhesins [PDF]

open access: yesJournal of Bacteriology, 2004
ABSTRACT Bacterial surface structures such as capsules and adhesins are generally regarded as important virulence factors. Here we demonstrate that capsules block the function of the self-recognizing protein antigen 43 through physical shielding.
Schembri, Mark A.   +2 more
openaire   +5 more sources

Adhesins as Targets for Vaccine Development

open access: yesEmerging Infectious Diseases, 1999
Blocking the primary stages of infection, namely bacterial attachment to host cell receptors and colonization of the mucosal surface, may be the most effective strategy to prevent bacterial infections. Bacterial attachment usually involves an interaction
Theresa M. Wizemann   +2 more
doaj   +1 more source

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