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Bacterial adhesins: function and structure
International Journal of Medical Microbiology, 2000 Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens. The fundamental processes that determine bacterial attachment to host tissue surfaces are mediated by microbial adhesins. Host specificity and tissue tropism are characteristics exhibited by different bacteria and are determined (at least in part) by ...
Klemm, Per, Schembri, Mark A.
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Bacterial Adhesins in Host-Microbe Interactions [PDF]
Cell Host & Microbe, 2009 Most commensal and pathogenic bacteria interacting with eukaryotic hosts express adhesive molecules on their surfaces that promote interaction with host cell receptors or with soluble macromolecules. Even though bacterial attachment to epithelial cells may be beneficial for bacterial colonization, adhesion may come at a cost because bacterial ...
Kline, Kimberly A. +4 more
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Capsule Shields the Function of Short Bacterial Adhesins [PDF]
Journal of Bacteriology, 2004 ABSTRACT Bacterial surface structures such as capsules and adhesins are generally regarded as important virulence factors. Here we demonstrate that capsules block the function of the self-recognizing protein antigen 43 through physical shielding.
Schembri, Mark A. +2 more
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Yersinia pseudotuberculosis-derived adhesins [PDF]
Инфекция и иммунитет, 2019 Around fifteen surface components referred to adhesins have been identified in Yersinia pseudotuberculosis combining primarily microbiological, molecular and genetic, as well as immunochemical and biophysical methods. Y.
A. A. Byvalov, I. V. Konyshev
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Adhesins as Targets for Vaccine Development
Emerging Infectious Diseases, 1999 Blocking the primary stages of infection, namely bacterial attachment to host cell receptors and colonization of the mucosal surface, may be the most effective strategy to prevent bacterial infections. Bacterial attachment usually involves an interaction
Theresa M. Wizemann +2 more
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An internal thioester in a pathogen surface protein mediates covalent host binding [PDF]
eLife, 2015 To cause disease and persist in a host, pathogenic and commensal microbes must adhere to tissues. Colonization and infection depend on specific molecular interactions at the host-microbe interface that involve microbial surface proteins, or adhesins.
Miriam Walden +14 more
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Adhesion and host cell modulation: critical pathogenicity determinants of
Parasites & Vectors, 2011 Bartonella henselae, the agent of cat scratch disease and the vasculoproliferative disorders bacillary angiomatosis and peliosis hepatis, contains to date two groups of described pathogenicity factors: adhesins and type IV secretion systems.
Kempf Volkhard AJ, Franz Bettina
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Identification of cell-binding adhesins of Leptospira interrogans. [PDF]
PLoS Neglected Tropical Diseases, 2014 Leptospirosis is a globally distributed bacterial infectious disease caused by pathogenic members of the genus Leptospira. Infection can lead to illness ranging from mild and non-specific to severe, with jaundice, kidney and liver dysfunction, and ...
Karen V Evangelista +5 more
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Binding of bacterial adhesins to rat glomerular mesangium in vivo [PDF]
Kidney International, 1993 Two well characterized bacterial adhesins, the O75X fimbriae of Escherichia coli and the type-3 fimbriae of Klebsiellae, with in vitro affinities to type IV and V collagens, respectively, were used to test whether bacterial components with affinity for glomerular matrix could bind to glomeruli in vivo.
Miettinen, Aaro +6 more
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Gut Microbes, 2022 Helicobacter pylori infection is associated with the development of several gastric diseases including gastric cancer. To reach a long-term colonization in the host stomach, H.
Kai-Wen Teng +12 more
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