Results 11 to 20 of about 23,814 (213)
Role of Hydration in Collagen Recognition by Bacterial Adhesins [PDF]
Protein-protein recognition regulates the vast majority of physiological or pathological processes. We investigated the role of hydration in collagen recognition by bacterial adhesin CNA by means of first principle molecular-dynamics samplings. Our characterization of the hydration properties of the isolated partners highlights dewetting-prone areas on
Vitagliano L, Berisio R, De Simone A
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Bacterial biofilms are formed on environmental surfaces and host tissues, and facilitate host colonization and antibiotic resistance by human pathogens.
Xin Huang +17 more
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Helicobacter pylori infection is associated with the development of several gastric diseases including gastric cancer. To reach a long-term colonization in the host stomach, H.
Kai-Wen Teng +12 more
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Identification of cell-binding adhesins of Leptospira interrogans. [PDF]
Leptospirosis is a globally distributed bacterial infectious disease caused by pathogenic members of the genus Leptospira. Infection can lead to illness ranging from mild and non-specific to severe, with jaundice, kidney and liver dysfunction, and ...
Karen V Evangelista +5 more
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Yersinia pseudotuberculosis-derived adhesins
Around fifteen surface components referred to adhesins have been identified in Yersinia pseudotuberculosis combining primarily microbiological, molecular and genetic, as well as immunochemical and biophysical methods. Y.
A. A. Byvalov, I. V. Konyshev
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Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. [PDF]
Pathogenic bacteria interacting with eukaryotic host express adhesins on their surface. These adhesins aid in bacterial attachment to the host cell receptors during colonization.
Sanjiv Kumar +4 more
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Bacterial adhesins: function and structure
Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens. The fundamental processes that determine bacterial attachment to host tissue surfaces are mediated by microbial adhesins. Host specificity and tissue tropism are characteristics exhibited by different bacteria and are determined (at least in part) by ...
Klemm, Per, Schembri, Mark A.
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Bacterial Adhesins in Host-Microbe Interactions [PDF]
Most commensal and pathogenic bacteria interacting with eukaryotic hosts express adhesive molecules on their surfaces that promote interaction with host cell receptors or with soluble macromolecules. Even though bacterial attachment to epithelial cells may be beneficial for bacterial colonization, adhesion may come at a cost because bacterial ...
Kline, Kimberly A. +4 more
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Capsule Shields the Function of Short Bacterial Adhesins [PDF]
ABSTRACT Bacterial surface structures such as capsules and adhesins are generally regarded as important virulence factors. Here we demonstrate that capsules block the function of the self-recognizing protein antigen 43 through physical shielding.
Schembri, Mark A. +2 more
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Adhesins as Targets for Vaccine Development
Blocking the primary stages of infection, namely bacterial attachment to host cell receptors and colonization of the mucosal surface, may be the most effective strategy to prevent bacterial infections. Bacterial attachment usually involves an interaction
Theresa M. Wizemann +2 more
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