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The Flo Adhesin Family [PDF]

open access: yesPathogens, 2021
The first step in the infection of fungal pathogens in humans is the adhesion of the pathogen to host tissue cells or abiotic surfaces such as catheters and implants. One of the main players involved in this are the expressed cell wall adhesins. Here, we
Ronnie G Willaert   +2 more
exaly   +7 more sources

FaaPred: A SVM-Based Prediction Method for Fungal Adhesins and Adhesin-Like Proteins [PDF]

open access: yesPLoS ONE, 2010
Adhesion constitutes one of the initial stages of infection in microbial diseases and is mediated by adhesins. Hence, identification and comprehensive knowledge of adhesins and adhesin-like proteins is essential to understand adhesin mediated ...
Dinesh Gupta, Jayashree Ramana
exaly   +5 more sources

Sticking to the Subject: Multifunctionality in Microbial Adhesins

open access: yesJournal of Fungi, 2023
Bacterial and fungal adhesins mediate microbial aggregation, biofilm formation, and adhesion to host. We divide these proteins into two major classes: professional adhesins and moonlighting adhesins that have a non-adhesive activity that is ...
Peter N. Lipke, Peleg Ragonis-Bachar
doaj   +2 more sources

mGem: Fungal adhesins in Candidozyma auris confer unique fitness for skin colonization [PDF]

open access: yesmBio
Candidozyma auris (formerly Candida auris) is an emerging multidrug-resistant fungal pathogen that causes life-threatening infections in humans. C. auris is distinct from other Candida species and exhibits exceptional capacity for skin colonization ...
Abishek Balakumar, Shankar Thangamani
doaj   +2 more sources

Context-dependent reprogramming of ALS adhesin expression in Candida albicans: a multi-inducer analysis linking morphogenesis to virulence plasticity [PDF]

open access: yesFrontiers in Microbiology
Candida albicans employs the ALS (Agglutinin-Like Sequence) gene family to encode cell-surface adhesins that are central to host colonization, tissue invasion, and biofilm formation.
Radfan Ahmed   +6 more
doaj   +2 more sources

Adhesins in the virulence of opportunistic fungal pathogens of human

open access: yesMycology, 2021
Aspergillosis, candidiasis, and cryptococcosis are the most common cause of mycoses-related disease and death among immune-compromised patients. Adhesins are cell-surface exposed proteins or glycoproteins of pathogens that bind to the extracellular ...
Amrita Kumari   +7 more
doaj   +1 more source

A novel class of Candida glabrata cell wall proteins with β-helix fold mediates adhesion in clinical isolates.

open access: yesPLoS Pathogens, 2021
Candida glabrata is an opportunistic pathogenic yeast frequently causing infections in humans. Though it lacks typical virulence factors such as hyphal development, C. glabrata contains a remarkably large and diverse set of putative wall adhesins that is
Viktoria Reithofer   +4 more
doaj   +1 more source

Special Issue “Sporothrix and Sporotrichosis 2.0”

open access: yesJournal of Fungi, 2022
Sporotrichosis is a chronic fungal disease of humans and other mammals that often affects the skin and subcutaneous tissues and, rarely, deep-seated organs (most frequently in immunocompetent hosts) [...]
Héctor M. Mora-Montes
doaj   +1 more source

Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. [PDF]

open access: yesPLoS ONE, 2013
Pathogenic bacteria interacting with eukaryotic host express adhesins on their surface. These adhesins aid in bacterial attachment to the host cell receptors during colonization.
Sanjiv Kumar   +4 more
doaj   +1 more source

The Role of Candida albicans Virulence Factors in the Formation of Multispecies Biofilms With Bacterial Periodontal Pathogens

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Periodontal disease depends on the presence of different microorganisms in the oral cavity that during the colonization of periodontal tissues form a multispecies biofilm community, thus allowing them to survive under adverse conditions or facilitate ...
Dorota Satala   +10 more
doaj   +1 more source

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