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The first step in the infection of fungal pathogens in humans is the adhesion of the pathogen to host tissue cells or abiotic surfaces such as catheters and implants. One of the main players involved in this are the expressed cell wall adhesins. Here, we
Ronnie G Willaert +2 more
exaly +7 more sources
FaaPred: A SVM-Based Prediction Method for Fungal Adhesins and Adhesin-Like Proteins [PDF]
Adhesion constitutes one of the initial stages of infection in microbial diseases and is mediated by adhesins. Hence, identification and comprehensive knowledge of adhesins and adhesin-like proteins is essential to understand adhesin mediated ...
Dinesh Gupta, Jayashree Ramana
exaly +5 more sources
Sticking to the Subject: Multifunctionality in Microbial Adhesins
Bacterial and fungal adhesins mediate microbial aggregation, biofilm formation, and adhesion to host. We divide these proteins into two major classes: professional adhesins and moonlighting adhesins that have a non-adhesive activity that is ...
Peter N. Lipke, Peleg Ragonis-Bachar
doaj +2 more sources
mGem: Fungal adhesins in Candidozyma auris confer unique fitness for skin colonization [PDF]
Candidozyma auris (formerly Candida auris) is an emerging multidrug-resistant fungal pathogen that causes life-threatening infections in humans. C. auris is distinct from other Candida species and exhibits exceptional capacity for skin colonization ...
Abishek Balakumar, Shankar Thangamani
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Context-dependent reprogramming of ALS adhesin expression in Candida albicans: a multi-inducer analysis linking morphogenesis to virulence plasticity [PDF]
Candida albicans employs the ALS (Agglutinin-Like Sequence) gene family to encode cell-surface adhesins that are central to host colonization, tissue invasion, and biofilm formation.
Radfan Ahmed +6 more
doaj +2 more sources
Adhesins in the virulence of opportunistic fungal pathogens of human
Aspergillosis, candidiasis, and cryptococcosis are the most common cause of mycoses-related disease and death among immune-compromised patients. Adhesins are cell-surface exposed proteins or glycoproteins of pathogens that bind to the extracellular ...
Amrita Kumari +7 more
doaj +1 more source
Candida glabrata is an opportunistic pathogenic yeast frequently causing infections in humans. Though it lacks typical virulence factors such as hyphal development, C. glabrata contains a remarkably large and diverse set of putative wall adhesins that is
Viktoria Reithofer +4 more
doaj +1 more source
Special Issue “Sporothrix and Sporotrichosis 2.0”
Sporotrichosis is a chronic fungal disease of humans and other mammals that often affects the skin and subcutaneous tissues and, rarely, deep-seated organs (most frequently in immunocompetent hosts) [...]
Héctor M. Mora-Montes
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Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. [PDF]
Pathogenic bacteria interacting with eukaryotic host express adhesins on their surface. These adhesins aid in bacterial attachment to the host cell receptors during colonization.
Sanjiv Kumar +4 more
doaj +1 more source
Periodontal disease depends on the presence of different microorganisms in the oral cavity that during the colonization of periodontal tissues form a multispecies biofilm community, thus allowing them to survive under adverse conditions or facilitate ...
Dorota Satala +10 more
doaj +1 more source

