Results 11 to 20 of about 26,776 (211)
The first step in the infection of fungal pathogens in humans is the adhesion of the pathogen to host tissue cells or abiotic surfaces such as catheters and implants. One of the main players involved in this are the expressed cell wall adhesins. Here, we
Ronnie G. Willaert +2 more
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A Tail of Phage Adhesins [PDF]
In this issue of Structure, Dunne et al. (2018) unveil the architecture of Salmonella phage S16 adhesin. The structure unravels a beads-on-a-string topology consisting of three domains of which the C-terminal glycine-rich PGII domain, located at the distal tip of the long tail fiber, mediates cell surface attachment and host recognition.
Nicholas A, Swanson, Gino, Cingolani
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Bone and joint infections (BJI) represent the second cause of invasive Group B Streptococcus (GBS) infections. Biofilm formation plays a major role in BJI. This study’s aim was to analyze the genetic features and biofilm production of GBS strains. In six
Marion Lacasse +9 more
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Post-translational processing targets functionally diverse proteins in Mycoplasma hyopneumoniae [PDF]
Mycoplasma hyopneumoniae is a genome-reduced, cell wall-less, bacterial pathogen with a predicted coding capacity of less than 700 proteins and is one of the smallest self-replicating pathogens. The cell surface of M.
Jessica L. Tacchi +10 more
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The Biology of Neisseria Adhesins [PDF]
Members of the genus Neisseria include pathogens causing important human diseases such as meningitis, septicaemia, gonorrhoea and pelvic inflammatory disease syndrome. Neisseriae are found on the exposed epithelia of the upper respiratory tract and the urogenital tract.
Christodoulides, Myron, Hung, Miao-Chiu
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The first step in the infection of humans by microbial pathogens is their adherence to host tissue cells, which is frequently based on the binding of carbohydrate-binding proteins (lectin-like adhesins) to human cell receptors that expose glycans.
Francesco S. Ielasi +6 more
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Single-Molecule Force Spectroscopy of Mycobacterial Adhesin-Adhesin Interactions [PDF]
ABSTRACT The heparin-binding hemagglutinin (HBHA) is one of the few virulence factors identified for Mycobacterium tuberculosis . It is a surface-associated adhesin that expresses a number of different activities, including mycobacterial adhesion to nonphagocytic cells and microbial aggregation.
Claire, Verbelen +4 more
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Yersinia pseudotuberculosis-derived adhesins
Around fifteen surface components referred to adhesins have been identified in Yersinia pseudotuberculosis combining primarily microbiological, molecular and genetic, as well as immunochemical and biophysical methods. Y.
A. A. Byvalov, I. V. Konyshev
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Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a major cause of foodborne gastrointestinal illness. The adhesion of EHEC to host tissues is the first step enabling bacterial colonization. Adhesins such as fimbriae and flagella mediate this process.
Hélène Cazzola +10 more
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Evolution of host-microbe cell adherence by receptor domain shuffling
Stable adherence to epithelial surfaces is required for colonization by diverse host-associated microbes. Successful attachment of pathogenic microbes to host cells via adhesin molecules is also the first step in many devastating infections.
EmilyClare P Baker +6 more
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