Results 171 to 180 of about 256,147 (309)

Structural Characterization of a Proto-Type Galectin from <i>Cinachyrella</i> sp. and Evaluation of Its Selective Bacterial Glycan Recognition and Antibiofilm Activity. [PDF]

Microorganisms
Marques JSN, Andrade FRN, Torres RCF, Barbosa Junior IF, Silva GSDD, Chaves RP, Malveira EA, Nascimento E, Pinheiro U, Vasconcelos MA, Texeira EH, Carneiro RF, Nagano CS, Sampaio AH.   +13 more
europepmc   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

LeGenD: High-throughput N-glycan profiling using explainable AI and lectin profiling. [PDF]

J Biol Chem
Li H, Peralta AG, Schoffelen S, Hansen AH, Arnsdorf J, Schinn SM, Skidmore J, Choudhury B, Rocamora F, Paulchakrabarti M, Voldborg BG, Chiang AWT, Lewis NE.   +12 more
europepmc   +1 more source

FOXC1: A Key Transcription Factor of VSMC‐Derived Foam Cell Formation in Atherosclerotic Plaque Instability

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian, Xue‐Ling Li, Li‐Hong Wang, Wei Yang, Yu Jiang   +4 more
wiley   +1 more source

Lectin-Directed Protein Aggregation Therapy toward Hyperfucosylated and Hypersialylated Metastatic Colorectal Cancers. [PDF]

Biomater Res
Han X, Li Y, Liu Y, Shen S, Shen Y, Zhang LS, Vong K.   +6 more
europepmc   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Neurohumoral aspects of energy metabolism regulation

Терапевтический архив, 2004
Т Yu Demidova, A S Ametov, A V Selivanova   +2 more
doaj  

Lectin-Fc(IgG2a) fusion proteins binding to the cell wall of <i>C. albicans</i> cause structural, metabolic, oxidative, and other pleiotropic effects. [PDF]

Microbiol Spectr
Mendoza SR, de La Noval CR, Ferreira MdS, Honorato L, Artunduaga Bonilla JJ, Ramos LFC, Domont G, Peralta JM, Nimrichter L, Guimarães AJ.   +9 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Receptor profiling and growth assessment of influenza A virus in porcine mammary and non-mammary tissues and derived cells. [PDF]

J Virol
Barron-Castillo U, Berube N, Swan CL, Javed MA, Aubrey L, Trann J, Gidych M, Shrivastava S, Baid K, Banerjee A, Zhou Y.   +10 more
europepmc   +1 more source