Results 241 to 250 of about 241,517 (312)

Garadacimab for the long‐term prophylaxis of hereditary angioedema

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün, Regina Treudler, Petra Staubach, Inmaculada Martinez Saguer, Thomas Linhoff, Markus Magerl   +5 more
wiley   +1 more source

Hematologic Glyco-Signatures: Emerging Blood-Based Sugar Codes Linked to Hyper-Aggressive Breast Cancer. [PDF]

Breast Cancer (Dove Med Press)
Obeagu EI.
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Complement Dysregulation in Kidney Diseases: Mechanisms, Biomarkers, and Emerging Targeted Therapies. [PDF]

Int J Mol Sci
Jesiołowski P, Krzywda M, Furmańczyk-Zawiska A, Durlik M.   +3 more
europepmc   +1 more source

Lectin-Based Antiviral Strategies for Porcine Reproductive and Respiratory Syndrome Virus 2 Infection: Griffithsin Suppresses Viral Replication In Vitro and Reduces Early Viremia In Vivo. [PDF]

Microorganisms
Kadekar D, Velayudhan D, Vinyeta E, Zhang J, Aljets E, Bamrung V, Sitthicharoenchai P, Michael A, Frogue K, Heng M, Liu A, Bongiorni C, Bhate M, Estell DA, Shen C, Poulsen C.   +15 more
europepmc   +1 more source

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID. [PDF]

Immunology
Keat SBK, Khatri P, Ali YM, Arachchilage CH, Demopulos G, Baillie K, Miners KL, Ladell K, Jones SA, Davies HE, Price DA, Zelek WM, Morgan BP, Schwaeble WJ, Lynch NJ.   +14 more
europepmc   +1 more source

Comparative analysis of clearing methods for 3D imaging of the vasculature in mineralized mouse tissues. [PDF]

iScience
Ishola AO, Pillai A, Ahn T, RE-JOIN Consortium, Hsu CW, Lee B, Haelterman N, Wythe JD.   +7 more
europepmc   +1 more source

GlycoChat Uncovers Glycan-Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer. [PDF]

Adv Sci (Weinh)
Anh DXT, Keisham S, Burramsetty A, Oinam L, Kumano K, Kuno A, Shimomura O, Oda T, Tateno H.   +8 more
europepmc   +1 more source