Results 41 to 50 of about 24,968 (283)
May salivary gland secretory proteins from hematophagous leeches (Hirudo verbana) reach pharmacologically relevant concentrations in the vertebrate host? [PDF]
Saliva of hematophagous leeches (Hirudo sp.) contains bioactive proteins which allow the leech proper feeding and storage of ingested blood, but may also exert effects in the host.
Sarah Lemke +4 more
doaj +1 more source
BackgroundAcute limb ischemia due to microvascular malperfusion may be refractory to initial therapies. Medicinal leech therapy (hirudotherapy) has been attempted in plastic and reconstructive surgery to improve venous congestion in ischemic flaps ...
Joseph C. Resch +4 more
doaj +1 more source
Medicinal Leech Therapy: Hirudotherapy
Hirudoterapy is a form of treatmentthat has been used to treat diseases for centuries using medicinal leeches.Leeches have been used therapeutically for many years, but their use hasdecreased as pharmacotherapy progresses. Today, a number of biologically andpharmacologically active bioactive substances have been identified in thesecretion of leeches ...
Ayhan, Hüseyin, Mollahaliloğlu, Salih
openaire +3 more sources
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Cronic venous insufficiency is an important and frequent disease, characterized by the retrograde flow of blood in the lower extremity, is a common, debilitating disorder that is increasing in prevalence. Leech therapy is a traditional healing method for
Tarık Sarı +2 more
doaj
Complementary Therapies Used Among Adult Patients with Type 2 Diabetes Mellitus in Aceh, Indonesia [PDF]
Purpose: This study aimed to reveal Complementary Therapies (CT) use among adult patients with type 2 diabetes mellitus (T2DM) in Aceh, Indonesia, and to determine the reasons of using the CT.Methods: A descriptive, cross-sectional study was undertaken ...
J, M. (Manasurakarn) +2 more
core
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine +14 more
wiley +1 more source
Pragmatic ability and disability as emergent phenomena [PDF]
A holistic approach to pragmatic ability and disability is outlined which takes account both of the behaviour of individuals involved in the communicative process, and also of the underlying factors which contribute to such behaviour.
Perkins, Michael R
core +1 more source
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source

