Results 41 to 50 of about 24,968 (283)

May salivary gland secretory proteins from hematophagous leeches (Hirudo verbana) reach pharmacologically relevant concentrations in the vertebrate host? [PDF]

open access: yesPLoS ONE, 2013
Saliva of hematophagous leeches (Hirudo sp.) contains bioactive proteins which allow the leech proper feeding and storage of ingested blood, but may also exert effects in the host.
Sarah Lemke   +4 more
doaj   +1 more source

Hirudotherapy for limb ischemia in the pediatric intensive care unit: A retrospective observational cohort

open access: yesFrontiers in Pediatrics, 2023
BackgroundAcute limb ischemia due to microvascular malperfusion may be refractory to initial therapies. Medicinal leech therapy (hirudotherapy) has been attempted in plastic and reconstructive surgery to improve venous congestion in ischemic flaps ...
Joseph C. Resch   +4 more
doaj   +1 more source

Medicinal Leech Therapy: Hirudotherapy

open access: yesAnkara Medical Journal, 2018
Hirudoterapy is a form of treatmentthat has been used to treat diseases for centuries using medicinal leeches.Leeches have been used therapeutically for many years, but their use hasdecreased as pharmacotherapy progresses. Today, a number of biologically andpharmacologically active bioactive substances have been identified in thesecretion of leeches ...
Ayhan, Hüseyin, Mollahaliloğlu, Salih
openaire   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

A Case That Was Not Detected Reflux Flow With Leech Therapy For 6 Months Follow-Up İn Venous İnsufficiency

open access: yesInternational Journal of Traditional and Complementary Medicine Research, 2020
Cronic venous insufficiency is an important and frequent disease, characterized by the retrograde flow of blood in the lower extremity, is a common, debilitating disorder that is increasing in prevalence. Leech therapy is a traditional healing method for
Tarık Sarı   +2 more
doaj  

Complementary Therapies Used Among Adult Patients with Type 2 Diabetes Mellitus in Aceh, Indonesia [PDF]

open access: yes, 2014
Purpose: This study aimed to reveal Complementary Therapies (CT) use among adult patients with type 2 diabetes mellitus (T2DM) in Aceh, Indonesia, and to determine the reasons of using the CT.Methods: A descriptive, cross-sectional study was undertaken ...
J, M. (Manasurakarn)   +2 more
core  

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Pragmatic ability and disability as emergent phenomena [PDF]

open access: yes, 2005
A holistic approach to pragmatic ability and disability is outlined which takes account both of the behaviour of individuals involved in the communicative process, and also of the underlying factors which contribute to such behaviour.
Perkins, Michael R
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

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