Results 91 to 100 of about 2,163,140 (357)

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

SpaBatch: Deep Learning‐Based Cross‐Slice Integration and 3D Spatial Domain Identification in Spatial Transcriptomics

Advanced Science, EarlyView.
SpaBatch is an end‐to‐end multi‐slice spatial transcriptomics data integration framework. It simultaneously performs embedding learning, spatial feature denoising and reconstruction, batch effect correction, and spatial domain optimization, effectively correcting batch effects and achieving accurate 3D spatial domain identification.
Jinyun Niu, Donghai Fang, Jinyu Chen, Yi Xiong, Juan Liu, Wenwen Min   +5 more
wiley   +1 more source

Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia‐Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling‐Mediated Neutrophil Extracellular Traps Formation

Advanced Science, EarlyView.
This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian, Yonghong Xiong, Junbiao Zhan, Zhikun Lu, Yuxi Zhang, Yan Leng, Qin Huang, Zhongyuan Xia   +7 more
wiley   +1 more source

A global benchmark of algorithms for segmenting the left atrium from late gadolinium-enhanced cardiac magnetic resonance imaging

Medical Image Anal., 2020
Zhaohan Xiong, Qing Xia, Zhiqiang Hu, Ning Huang, Cheng Bian, Yefeng Zheng, Sulaiman Vesal, N. Ravikumar, A. Maier, Xin Yang, P. Heng, Dong Ni, Caizi Li, Qianqian Tong, Weixin Si, É. Puybareau, Younes Khoudli, T. Géraud, Chen Chen, Wenjia Bai, D. Rueckert, Lingchao Xu, X. Zhuang, Xinzhe Luo, Shuman Jia, Maxime Sermesant, Yashu Liu, Kuanquan Wang, D. Borra, Alessandro Masci, C. Corsi, Coen de Vente, M. Veta, R. Karim, C. J. Preetha, S. Engelhardt, Menyun Qiao, Yuanyuan Wang, Q. Tao, M. Nuñez-Garcia, O. Camara, N. Savioli, P. Lamata, Jichao Zhao   +43 more
semanticscholar   +1 more source

An Opto‐Bio‐Hydrodynamic Platform for Instructing Cardiac Left‐Right Asymmetry Development

Advanced Science, EarlyView.
By establishing mechanistic links among optically tuned ciliary dynamics, flow‐mediated signaling, and organ asymmetry, a multifunctional Opto‐Bio‐Hydrodynamic platform is developed to modulate ciliary motion with the programmable near infrared light for instructing cardiac left‐right asymmetry development in a spatiotemporally controlled manner, which
Haifeng Qin, Xiaoshuai Liu, Yufeng Lin, Guangyi Yang, Haojiang Ren, Mingyuan Cao, Zhenheng Jiao, Baojun Li, Xianchuang Zheng   +8 more
wiley   +1 more source

Myxoma of the Left Atrium [PDF]

, 1957
E. F. Chin, D. N. Ross
openalex   +1 more source

Myxoma of the Left Atrium [PDF]

Proceedings of the Royal Society of Medicine, 1962
Hugh Smellie, R S Bruce Pearson
openaire   +3 more sources

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

ISOLATED DRAINAGE OF THE INFERIOR VENA CAVA TO THE LEFT ATRIUM [PDF]

, 1963
A. W. Venables
openalex   +1 more source

Parametric Design of Continuum Robots Using Interlocking Ball Joints

Advanced Intelligent Systems, EarlyView.
Herein, a parametric design methodology is introduced for producing a wide variety of modular ball joint‐based continuum robots. It is demonstrate by designing a magnetically actuated continuum robot for cardiac ablations. The methodology is released as an open‐source computer‐assisted design extension that automatically designs continuum robots based ...
Alexandre Mesot, Quentin Boehler, Florian Heemeyer, Sean Lyttle, Buse Aktaş, Bradley J. Nelson   +5 more
wiley   +1 more source