Results 91 to 100 of about 2,090,027 (300)
Advanced Science, EarlyView.Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu +5 more
wiley +1 more source
Minimally Invasive Approach to Correct Anomalous Inferior Vena Cava Connection to the Left Atrium
, 2017 Anomalous drainage of the inferior vena cava into the left atrium is a rare congenital condition. A 20-year-old girl was referred for recurrent transient ischemic attacks.
Davide Marini +5 more
core +1 more source
Advanced Science, EarlyView.An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin +18 more
wiley +1 more source
Thickness‐Gradient Liquid Metal Connectors for Seamless Electrophysiological Sensors
Advanced Science, EarlyView.Thickness‐gradient liquid metal interfaces with elastomeric substrates enable seamless integration between ultrathin skin‐conformal electrodes and external interconnects. The mechanically compliant connector reduces interfacial mismatch and supports stable ECG/EMG monitoring under bending and motion.
Jinyoung Kim +3 more
wiley +1 more source
Apelin and heart remodeling in patients with abdominal obesity
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2015 To evaluate plasma concentration of apelin and its correlation with structural and functional heart parameters in patients with abdominal obesity. 93 patients with abdominal obesity (criteria IDF, 2005) and 21 healthy people at the ages from 25 to 57 ...
O. V. Listopad +4 more
doaj +1 more source
A novel technique for giant left atrium reduction.
, 2001 We herein describe a safe and reproducible technique for left atrial volume reduction in patients with a giant left atrium. In a 56-year-old patient undergoing redo mitral valve replacement, the left atrium measured 18 x 20 x 17 cm occupying the middle ...
I. Pulitani +6 more
core +1 more source
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
Advanced Science, EarlyView.UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
Malignant phyllodes tumor of the left atrium
, 2014 Metastatic tumors to the heart usually involve right sided chambers. We report a rare case of malignant phyllodes tumor of breast with metastatic involvement of left atrium occurring through direct invasion from mediastinal micro-metastasis and ...
Vital Rangashamanna +8 more
core +1 more source
Review of Pitx2-insufficiency induced remodelling data and model parameters in human left atrium.
, 2020 Review of Pitx2-insufficiency induced remodelling data and model parameters in human left atrium.
Jieyun Bai (7525148) +5 more
core +1 more source
Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation
Advanced Science, EarlyView.Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu +10 more
wiley +1 more source