Results 131 to 140 of about 1,881,139 (280)
An equation with left and right fractional derivatives
Publications de l'Institut Mathematique, 2006 We consider an equation with left and right fractional derivatives and with the boundary condition y(0) = lim x?0+ y(x) = 0, y(b) = lim x?b? y(x) = 0 in the space L1(0, b) and in the subspace of tempered distributions. The asymptotic behavior of solutions in the end points 0 and b have been specially analyzed by using Karamata?s regularly varying ...
openaire +3 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Prolific domains and the left periphery [PDF]
, 2013 The left periphery has enjoyed extensive study over the past years, especially drawn against the framework of Rizzi (1997). It is argued that in this part of the clause, relations are licensed that have direct impact on discourse interpretation and ...
Grohmann, Kleanthes K.
core
Journal of MathematicsIn this study, we investigate the behavior of semiprime ideals that satisfy certain algebraic identities using multiplicative (generalized) derivations. In addition, examples are provided to show that the limits imposed on the hypotheses of the different
Amal S. Alali +4 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Functional network activation during a subtraction task
Scientific ReportsArithmetic processing recruits fronto-parietal and temporal networks with frequency-specific dynamics modulated by operation and complexity. However, spectral and connectivity dynamics underlying individual differences in arithmetic performance remain ...
Anna Hutber +4 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source