Results 231 to 240 of about 2,290,678 (288)

CKMT1 Counteracts VDAC1 Oligomerization‐Induced Neuronal Pyroptosis Through Steric Hindrance in Ischemic Stroke

Advanced Science, EarlyView.
CKMT1 inhibits VDAC1 oligomerization via a dual‐region mechanism: its NTD interacts with the VDAC1 C‐terminal domain, while residues 1–39 sterically hinder dimerization, thereby reducing mtDNA leakage and AIM2 inflammasome activation, suppressing neuronal pyroptosis and protecting against cerebral ischemic injury. ABSTRACT Ischemic stroke is one of the
Xiaoyu Wang, Sai Shi, Jianghui Wu, Jingge Zhang, Shuqin Li, Yuyan Hu, Haifeng Yin, Chenguang Zhao, Dong Ma, Xiaohui Xian, Lizhe Liu, Ling Zhao, Xiyun Liu, Zhikai Yu, Lihua Dong, Wenbin Li, Lingyan Zhang, Min Zhang   +17 more
wiley   +1 more source

Venoarterial Extracorporeal Membrane Oxygenation for Calcium Channel Blocker Toxicity: Does the Left Ventricle Matter? [PDF]

ASAIO J
Green A, Green A, Estrella A, Noel C.
europepmc   +1 more source

Cardiac Endothelial Enhancer RNA Tek‐e1 Restores Microvascular Homeostasis After Myocardial Infarction

Advanced Science, EarlyView.
Hypoxia‐induced KDM5A downregulation establishes a distinct endothelial repair programme, increasing H3K4me3 at the Tek promoter and intronic enhancer, enabling ISL1 to coordinately activate Tek transcription and induce enhancer‐RNA Tek‐e1. This cis‐regulatory RNA is essential for additional Tek/TIE2 induction through R‐loop formation and reinforced ...
Yang Lyu, Kun Yang, Yunzhi Ling, Jiahui Cheng, Jiaran Shi, Shiyu Hu, Changyi Zhou, Wei Wei, Hanchuan Chen, Xiang Wei, Zengru Wang, Zhi Xiong, Chenxi Yang, Su Zou, Rui Shen, Yuanyue Song, Gaofeng Zhang, Rifeng Gao, Kaiyang Lin, Yingjia Xu   +19 more
wiley   +1 more source

Impact of small left ventricle on paroxysmal atrial fibrillation ablation. [PDF]

Medicine (Baltimore)
Pang Z, Wang T, Jia Y.
europepmc   +1 more source

Acute lower limb ischemia due to embolism in a patient with severe aortic stenosis and thrombus in the left ventricle. [PDF]

Postepy Kardiol Interwencyjnej
Kwiatkowska E, Niedbał K, Okarski M, Legutko J, Kleczyński P.   +4 more
europepmc   +1 more source

When Patent Foramen Ovale (PFO) Can Cause Trouble-A Misplacement of Pacemaker Lead Into the Left Ventricle. [PDF]

Case Rep Cardiol
Helal A, Antoun I, El-Din M, Farooq M.
europepmc   +1 more source

Impact of Device Insertion Technique on Impella CP Position and Orientation Within the Left Ventricle. [PDF]

JACC Adv
Baldetti L, Beneduce A, Vanwersch C, Sonntag SJ, Ferreira de Almeida D, Knabe M, Nix C, Richter A, Maisano F, Scandroglio AM.   +9 more
europepmc   +1 more source

An infant case of double-chambered left ventricle with extensive non-compaction revealed by intraoperative endoscopy. [PDF]

J Cardiol Cases
Ifuku T, Okada N, Irisa H, Oshima Y.
europepmc   +1 more source

Surgical resection of primary cardiac fibroma of the left ventricle in an adult woman: case report. [PDF]

Eur Heart J Case Rep
Long NP, Hoang MNT, Nam PT, Dat PQ.
europepmc   +1 more source