Results 91 to 100 of about 58,634 (303)

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Displacement of impella post chest compressions

Heart Views, 2014
The Impella is a left ventricular assist device which is implanted via the transcutaneous femoral route and is placed across the aortic valve into the left ventricle.
Sourabh Aġġarwal, Susan Bannon
doaj   +1 more source

Significance of myocardial tenascin-C expression in left ventricular remodelling and long-term outcome in patients with dilated cardiomyopathy [PDF]

, 2015
Aim Dilated cardiomyopathy (DCM) has a variety of causes, and no useful approach to predict left ventricular (LV) remodelling and long-term outcome has yet been established.
Anzai, T, Ikeda, Y, Ishibashi-Ueda, H, Matsuyama, T-A, Nagai, T, Nakatani, T, Nakayama, T, Ogawa, H, Ohta-Ogo, K, Sugano, Y, Takeishi, Y, Yasuda, S, Yokokawa, T   +12 more
core   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

The impact of peripheral arterial disease on patients with mechanical circulatory support. [PDF]

, 2020
Background: Left ventricular assist devices (LVAD) are indicated as bridging or destination therapy for patients with advanced (Stage D) heart failure and reduced ejection fraction (HFrEF). Due to the clustering of the mutual risk factors, HFrEF patients
Ajmal, Rasikh, Al-Khadra, Yasser, Alraies, M Chadi, Asfour, Abedelrahim, Darmoch, Fahed, Gardi, Delair, Glazier, James, Mir, Tanveer, Moussa-Pacha, Homam, Sattar, Yasar, Ullah, Waqas   +10 more
core   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

The effect of transfusion of blood products on ventricular assist device support outcomes

ESC Heart Failure, 2020
Aims Perioperative blood transfusions are common among patients undergoing left ventricular assist device (LVAD) implantation. The association between blood product transfusion at the time of LVAD implantation and mortality has not been described ...
Supriya Shore, Thomas C. Hanff, Jeremy A. Mazurek, Matthew Seigerman, Robert Zhang, Edward W. Grandin, Esther Vorovich, Paul Mather, Caroline Olt, Jessica Howard, Joyce Wald, Michael A. Acker, Lee R. Goldberg, Pavan Atluri, Kenneth B. Margulies, J. Eduardo Rame, Edo Y. Birati   +16 more
doaj   +1 more source

Amiodarone-Induced Thyrotoxicosis and Ventricular Arrhythmias: Case Report and Review of the Literature [PDF]

, 2016
INTRODUCTION Amiodarone is a common drug used to treat arrhythmias and its side effects are diverse. An important adverse effect is amiodarone-induced thyrotoxicosis (AIT), which can potentially lead to a pro-arrythmogenic state. There have been limited
Shah, MD, Ashish
core   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Discovering Interpretable Semantics from Radio Signals for Contactless Cardiac Monitoring

Advanced Science, EarlyView.
This study presents a semantic representation framework for clinically interpretable cardiac monitoring from contactless radio signals. It formulates radio semantic learning as an information‐bottleneck problem and approximates the objective via intra‐modal compression and cross‐modal alignment, structuring radio measurements into meaningful semantic ...
Jinbo Chen, Haoyu Wang, Guixin Xu, Yuqin Yuan, Xinmeng Cai, Zhengwu Wei, Dongheng Zhang, Qibin Sun, Tianwei Zhang, Cuntai Guan, Yan Chen   +10 more
wiley   +1 more source