Results 71 to 80 of about 3,843,014 (290)

Mechanism design of ventricular assist device [PDF]

, 2016
This research presents an innovative design approach for the development of high efficiency Ventricular assist device that can be used for long-term support a heart failure patient.
Bumrungpetch, Jeerasit
core  

Synchrony relationships between the left ventricle and a left ventricular assist device: an experimental study in pigs

, 2012
Background: Synchronization between the left ventricle and a left ventricular assist device (LVAD) may be important for ventricular unloading and coronary perfusion.
Otero, Javier, Cañizo López, Juan Francisco Del, Heredero, Ángeles, Rodríguez Martínez, Daniel, PérezCaballero, Ramón, Quintana Villamandos, María Begoña, Rodríguez Bernal, Guillermo Juan, González Pinto, Ángel Tomás, Ruiz Fernández, Manuel   +8 more
core   +1 more source

Frank-starling control of a left ventricular assist device [PDF]

, 2011
A physiological control system was developed for a rotary left ventricular assist device (LVAD) in which the target pump flow rate (LVADQ) was set as a function of left atrial pressure (LAP), mimicking the Frank-Starling mechanism.
Stevens, Michael Charles, Pearcy, Mark J., Salamonsen, Robert F., M. Pearcy, Timms, Daniel L., N. R. Gaddum, Gaddum, Nicholas Richard, D. G. Mason, Fraser, John F., Mason, David G, M. C. Stevens, Pearcy, Mark, Salamonsen, Robert, Stevens, Michael, D. L. Timms, R. F. Salamonsen, Mason, David Glen, Timms, Daniel Lee, J. F. Fraser, Fraser, John   +19 more
core   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Treating myocardial stunning randomly, with either propofol or isoflurane following transient coronary occlusion and reperfusion in pigs

Annals of Cardiac Anaesthesia, 2009
Propofol and isoflurane may be used during fast track anesthesia for off-pump bypass, where transient ischemia is common. The purpose of this study was to compare the effects of propofol vs isoflurane in a porcine model of acute coronary occlusion ...
Urdaneta Felipe, Lobato Emilio, Kirby David, Sidi Avner   +3 more
doaj  

Ablation of ventricular tachycardia in a patient with a left ventricular assist device

Türk Kardiyoloji Derneği Arşivi, 2020
The use of a left ventricular assist device (LVAD) as a bridge to heart transplantation (HTx) or as a destination therapy in patients with a contraindication for HTx is increasing.
Evrim Şimşek, Emin Evren Özcan, Emre Demir, Pelin Öztürk, Sanem Nalbantgil   +4 more
doaj   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

A Multidisciplinary Approach to Electrical Instability and Cardiogenic Shock in Acute Myocardial Infarction

JACC: Case Reports, 2020
New cardiogenic shock classifications allow prompt recognition and management of complications of acute coronary syndrome. A 59-year-old man presented after a delayed left anterior descending coronary artery ST-segment elevation myocardial infarction in ...
Shuktika Nandkeolyar, MD, Tahmeed Contractor, MD, Rahul Bhardwaj, MD, Ravi Mandapati, MD, Antoine Sakr, MD, Islam Abudayyeh, MD, Anees Razzouk, MD, Aditya Satish Bharadwaj, MD   +7 more
doaj   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source