Results 61 to 70 of about 58,634 (303)

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian   +5 more
wiley   +1 more source

Conservative Management of LVAD-Associated Ventricular Pseudoaneurysm

open access: yesMethodist DeBakey Cardiovascular Journal
Left ventricular assist devices (LVAD) are surgically implanted mechanical support devices utilized with increasing frequency as a bridge to myocardial recovery, destination therapy, and heart transplantation.
Marvin Kajy   +4 more
doaj   +1 more source

Left ventricular assist device bioinformatics identify possible hubgenes and regulatory networks involved in the myocardium of patients with left ventricular assist device

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectiveThe aim of this study was to clarify the changes of myocardial gene expression profile after left ventricular assist device (LVAD) implantation and the related molecular biological significance.MethodsA thorough bioinformatic analysis to ...
Maryam Ajmal   +7 more
doaj   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

open access: yesAdvanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco   +7 more
wiley   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Postoperative care of 14 patients with left ventricular assist devices: a case series

open access: yesJournal of International Medical Research
A left ventricular assist device is a mechanical device that is surgically implanted in the heart to partially or completely replace the function of the heart.
Shenmin Wan   +3 more
doaj   +1 more source

Surface mapping demonstrates compatibility of implantable loop monitor with a continuous‐flow left ventricular assist device

open access: yesESC Heart Failure, 2021
Syncope in patients with continuous‐flow left ventricular assist device may be associated with arrhythmia and difficult to determine without an implantable cardioverter defibrillator.
Angela Li   +3 more
doaj   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee   +7 more
wiley   +1 more source

Implication of Hemodynamic Assessment during Durable Left Ventricular Assist Device Support

open access: yesMedicina, 2020
Durable left ventricular assist device therapy has improved survival in patients with advanced heart failure refractory to conventional medical therapy, although the readmission rates due to device-related comorbidities remain high.
Teruhiko Imamura, Nikhil Narang
doaj   +1 more source

Occupational Therapy’s Role with Ventricular Assist Devices and the Promotion of Travel Protocols [PDF]

open access: yes, 2020
An option for individuals diagnosed with end-stage heart failure is to receive a ventricular assist device (VAD). In 2006, Shepherd and Wilding produced an article regarding occupational therapy’s role during the VAD process as they anticipated a growing
Chandra, Natasha, Suplicki, Linda
core   +1 more source

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