Results 91 to 100 of about 4,399,583 (292)
Continuous‐flow left ventricular assist devices: Management in the emergency department
Journal of the American College of Emergency Physicians Open, 2020 With an increasing number of left ventricular assist devices (LVADs) being placed every year, emergency clinicians are increasingly likely to encounter them in their practice.
Maxwell A. Hockstein
doaj +1 more source
Design, development and evaluation of centrifugal ventricular assist devices [PDF]
, 2005 Heart disease is the developed world's biggest killer, and the shortage of donor hearts has accelerated the development of mechanical alternatives. \ud \ud Scientists, engineers and clinicians have attempted to replicate the human heart with a mechanical
Timms, Daniel Lee
core
Advanced Science, EarlyView.Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem +24 more
wiley +1 more source
Advanced Science, EarlyView.A damage‐free iCVD fluoropolymer passivation strategy is introduced for ambipolar vertical OECTs. Vapor‐phase infiltration and thermal annealing induce nanoscale phase separation in the OMIEC channel, enhancing overall device performance. A single‐channel bipolar event‐driven spiking encoder is also demonstrated for electrocardiogram signal encoding ...
Junyeong Yang +7 more
wiley +1 more source
Advanced Science, EarlyView.MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han +24 more
wiley +1 more source
Left Ventricular Assist Devices and Renal Ramifications
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Ajith Nair, Harveen Lamba
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Updates on management of advanced heart failure
Southwest Respiratory and Critical Care Chronicles, 2017 Advanced heart failure defines a subset of patients with heart failure with reduced ejection fraction having severe symptoms despite usual recommended therapy.
Hatice Duygu Bas +2 more
doaj +1 more source
TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains
Advanced Science, EarlyView.Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang +14 more
wiley +1 more source
Percutaneous ventricular assist devices for cardiogenic shock
, 2008 Cardiogenic shock complicates up to 7% of ST-segment elevation myocardial infarctions and 2.5% of non-ST-segment elevation myocardial infarctions, with an associated mortality of 50% to 70%.
Windecker, Stephan, Cook, Stéphane
core
Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications
Advanced Science, EarlyView.Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen +11 more
wiley +1 more source