Results 81 to 90 of about 4,399,583 (292)

Postoperative outcomes following rehabilitation in patients with left ventricular assist devices

Monaldi Archives for Chest Disease, 2020
Postoperative rehabilitation is a cornerstone of the recovery pathway following left ventricular assist device implantation (LVAD), and patients are expected to conduct an autonomous life thanks to improved technology and increased knowledge of ...
Massimiliano Polastri, Silvia Boschi, Giorgia Brillanti, Sofia Martin-Suarez, Marco Masetti, Luciano Potena, Antonio Loforte   +6 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Emergent decommissioning of HeartMate 3 for life-threatening hemorrhage

Journal of Vascular Surgery Cases and Innovative Techniques
Left ventricular assist devices are known for the treatment of heart failure. We present a patient who underwent emergent decommissioning of his left ventricular assist device after experiencing life-threatening hemorrhage.
Reginald E. Du, MD, Ryan S. Bedi, MD, W. Charles Sternbergh, III, MD, Aditya Bansal, MD   +3 more
doaj   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Outcomes of patients with continuous flow left ventricular assist device undergoing emergency endovascular treatment for atraumatic bleeding

CVIR Endovascular, 2019
Introduction Severe spontaneous bleeding is a significant complication in patients with continuous flow left ventricular assist devices; there is little evidence on endovascular treatment to support its use.
Valentina Bernardinello, Giulio Barbiero, Michele Battistel, Caterina Dengo, Roberto Stramare, Giulio Folino, Jonida Bejko, Massimiliano Carrozzini, Vincenzo Tarzia, Gino Gerosa, Tomaso Bottio   +10 more
doaj   +1 more source

Finite Element Driven Design Domain Identification of a Beating Left Ventricular Simulator

Bioengineering, 2019
Almost ten percent of the American population have heart diseases. Since the number of available heart donors is not promising, left ventricular assist devices are implemented as bridge therapies.
Utku Gulbulak, Atila Ertas
doaj   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Postoperative care of 14 patients with left ventricular assist devices: a case series

Journal of International Medical Research
A left ventricular assist device is a mechanical device that is surgically implanted in the heart to partially or completely replace the function of the heart.
Shenmin Wan, Yihong Chen, Xia Yuan, Ying Lin   +3 more
doaj   +1 more source

Palliative Medicine Consultation for Preparedness Planning in Patients Receiving Left Ventricular Assist Devices as Destination Therapy

, 2011
To assess the benefit of proactive palliative medicine consultation for delineation of goals of care and quality-of-life preferences before implantation of left ventricular assist devices as destination therapy (DT)
Mueller, Paul S, Park, Soon J, Barry A. Boilson, Carter, Kari A, Boilson, Barry A, Ottenberg, Abigale L, Keith M. Swetz, Swetz, Keith M, Freeman, Monica R, Paul S. Mueller, Monica R. Freeman, Kari A. Carter, AbouEzzeddine, Omar F, Omar F. AbouEzzeddine, Soon J. Park, Abigale L. Ottenberg   +15 more
core   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source