Results 181 to 190 of about 176,565 (312)

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

open access: yesInterdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen   +12 more
wiley   +1 more source

Echocardiographic assessment of inappropriate left ventricular mass and left ventricular hypertrophy in patients with diastolic dysfunction

open access: yesJournal of Research in Medical Sciences, 2012
Background: early diagnosis of left ventricular mass (LVM) inappropriateness and left ventricular hypertrophy (LVH) can result in preventing diastolic left ventricular dysfunction and its related morbidity and mortality.
Hasan Shemirani   +4 more
doaj  

Upregulating Compliant Titin in the Heart Attenuates Left Ventricular Stiffness in a Mouse Model with Diastolic Dysfunction [PDF]

open access: bronze, 2016
Mei Methawasin   +5 more
openalex   +1 more source

Investigation Into the Utility of 3D Speckle‐Tracking Echocardiography in Detecting Coronary Artery Microcirculation Dysfunction in Ischemia With Non‐Obstructive Coronary Artery Disease

open access: yesJournal of Clinical Ultrasound, EarlyView.
By detecting the subtle regional contractile dysfunction, 3D‐STE can efficiently distinguish CMCD and present a novel strategy for diagnosing INOCA. ABSTRACT Aim To assess the utility of three‐dimensional speckle‐tracking echocardiography (3D‐STE) in detecting coronary artery microcirculation dysfunction (CMCD) with non‐obstructive coronary artery ...
Yuexia Ma   +5 more
wiley   +1 more source

Comparative diagnostic accuracy study of point of care ultrasound techniques for detection of left atrial enlargement by hospital medicine physicians from archived echocardiogram images

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Left atrial enlargement (LAE) is predictive of cardiovascular morbidity and mortality. Prior studies of point‐of‐care ultrasound (POCUS) interpretation methods for identifying LAE utilized older echocardiographic reference ranges. Objectives Compare the test characteristics of hospitalist‐performed POCUS techniques for identifying ...
Christopher J. Smith   +7 more
wiley   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran   +5 more
wiley   +1 more source

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