Results 201 to 210 of about 173,276 (306)

6‐Shogaol Attenuates Doxorubicin‐Induced Cardiac and Skeletal Muscle Atrophy by Inhibiting E3 Ubiquitin Ligases and Necroptosis

open access: yesPhytotherapy Research, EarlyView.
Doxorubicin induces cardiac and skeletal muscle atrophy by upregulating E3 ubiquitin ligases, inhibiting myogenic regulatory factors, and activating necroptosis. Cardiac atrophy can further exacerbate cardiotoxicity. 6‐Shogaol negatively regulates these processes and attenuates doxorubicin‐induced cardiac and skeletal muscle atrophy.
Xipeng Sun   +5 more
wiley   +1 more source

Sympatho‐Excitation in Pulmonary Hypertension: The Potential Role of Pulmonary Arterial Baroreceptors: An Acute Physiologic Intervention Study

open access: yesRespirology, EarlyView.
Pulmonary arterial baroreceptors reflexively stimulate sympathetic nerve activity (SNA) in response to elevated pulmonary artery pressure and distension. In pulmonary hypertension patients, changes in muscle SNA were proportional to changes in pulmonary haemodynamics following nebulised iloprost.
Michael J. Plunkett   +6 more
wiley   +1 more source

Metabolic syndrome, left ventricular diastolic dysfunction and heart failure with preserved ejective fraction. [PDF]

open access: yesFront Endocrinol (Lausanne)
Zhou D   +7 more
europepmc   +1 more source

Data privacy model using blockchain reinforcement federated learning approach for scalable internet of medical things

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
Abstract Internet of Medical Things (IoMT) has typical advancements in the healthcare sector with rapid potential proof for decentralised communication systems that have been applied for collecting and monitoring COVID‐19 patient data. Machine Learning algorithms typically use the risk score of each patient based on risk factors, which could help ...
Chandramohan Dhasaratha   +9 more
wiley   +1 more source

4D flow MRI-based grading of left ventricular diastolic dysfunction: a validation study against echocardiography. [PDF]

open access: yesEur Radiol
Reiter C   +6 more
europepmc   +1 more source

Impaired Right, Left, or Biventricular Function and Resting Oxygen Saturation Are Associated With Mortality in Eisenmenger Syndrome: A Clinical and Cardiovascular Magnetic Resonance Study. [PDF]

open access: yes, 2015
Babu-Narayan, SV   +9 more
core   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

open access: yesAndrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Identification of Autologous Tissue Sources and Optimization of a Treatment Method for Intraoperative Manufacturing of Heart Valve Constructs

open access: yesArtificial Organs, EarlyView.
The use of autologous connective tissue, such as pericardium or peritoneum, combined with controlled tissue treatment, has the potential to result in a more durable heart valve prosthesis than current commercial prostheses. ABSTRACT Introduction Valvular heart disease remains a leading cause of morbidity and mortality. Current biological and mechanical
Marvin Steitz   +17 more
wiley   +1 more source

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